Literature DB >> 4366773

The mechanism of viral replication. Structure of replication complexes of encephalomyocarditis virus.

S S Thach, D Dobbertin, C Lawrence, F Golini, R E Thach.   

Abstract

The structure of the purified replicative intermediate of encephalomyocarditis virus was determined by electron microscopy. Approximately 80% of the replicative intermediate complexes were characterized by a filament of double-stranded RNA of widely variable length, which had a "bush" of single-stranded RNA at one end. In many examples one or more additional single-stranded bushes were appended internally to the double-stranded RNA filament. These results support the view that before deproteinization, replicative intermediate contains little if any double-stranded RNA.

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Year:  1974        PMID: 4366773      PMCID: PMC388497          DOI: 10.1073/pnas.71.6.2549

Source DB:  PubMed          Journal:  Proc Natl Acad Sci U S A        ISSN: 0027-8424            Impact factor:   11.205


  13 in total

1.  Studies on protein and nucleic acid metabolism in virus-infected mammalian cells. 1. Encephalomyocarditis virus in Krebs II mouse-ascites-tumour cells.

Authors:  E M MARTIN; J MALEC; S SVED; T S WORK
Journal:  Biochem J       Date:  1961-09       Impact factor: 3.857

2.  Circularity and cross-linking in preparations of replicative form of encephalomyocarditis virus RNA.

Authors:  V I Agol; L I Romanova; I M Cumakov; L D Dunaevskaya; A A Bogdanov
Journal:  J Mol Biol       Date:  1972-12-14       Impact factor: 5.469

3.  Architecture of the poliovirus replicative intermediate RNA.

Authors:  T Savage; N Granboulan; M Girard
Journal:  Biochimie       Date:  1971       Impact factor: 4.079

4.  Stability of polycation-induced cell competence for infection by viral RNA.

Authors:  G Koch
Journal:  Virology       Date:  1971-09       Impact factor: 3.616

5.  Poliovirus replicative intermediate: structural basis of infectivity.

Authors:  J M Bishop; G Koch; B Evans; M Merriman
Journal:  J Mol Biol       Date:  1969-12-14       Impact factor: 5.469

6.  Infectious replicative intermediate of poliovirus: purification and characterization.

Authors:  J M Bishop; G Koch
Journal:  Virology       Date:  1969-04       Impact factor: 3.616

7.  An intermediate in the synthesis of poliovirus RNA.

Authors:  D Baltimore; M Girard
Journal:  Proc Natl Acad Sci U S A       Date:  1966-08       Impact factor: 11.205

8.  Structure of the poliovirus replicative intermediate RNA.

Authors:  D Baltimore
Journal:  J Mol Biol       Date:  1968-03-14       Impact factor: 5.469

9.  Replication of viral nucleic acids. I. Enzyme-RNA complexes involved in the synthesis of Q-beta RNA.

Authors:  K Hori
Journal:  Biochim Biophys Acta       Date:  1970-10-15

10.  In vitro synthesis of phage RNA: the nature of the intermediates.

Authors:  C Weissmann; G Feix; H Slor
Journal:  Cold Spring Harb Symp Quant Biol       Date:  1968
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  3 in total

1.  Reaction of poliovirus RNAs with antibodies to double-stranded RNA demonstrated by an immunochemical binding assay.

Authors:  J R Miller; L A Calliguiri; J Tamm
Journal:  J Virol       Date:  1975-08       Impact factor: 5.103

2.  Interferon action: binding of viral RNA to the 40-kilodalton 2'-5'-oligoadenylate synthetase in interferon-treated HeLa cells infected with encephalomyocarditis virus.

Authors:  G Gribaudo; D Lembo; G Cavallo; S Landolfo; P Lengyel
Journal:  J Virol       Date:  1991-04       Impact factor: 5.103

3.  An analysis of tobacco mosaic virus replicative structures synthesized in vitro.

Authors:  N D Young; M Zaitlin
Journal:  Plant Mol Biol       Date:  1986-11       Impact factor: 4.076

  3 in total

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