Literature DB >> 4365579

Mechanism of enzymic acetylation of des-acetyl citrate lyase.

H Schmellenkamp, H Eggerer.   

Abstract

A new enzyme, acetate:SH-[acyl-carrier-protein] enzyme ligase (AMP), has been purified about 30-fold from cell-free extracts of Klebsiella aerogenes. The enzyme, in the presence of acetate and ATP, catalyzes the acetylation of enzymically inactive des-acetyl citrate lyase to enzymically active citrate lyase (EC 4.1.3.6). Acetate and ATP could be replaced by acetyl adenylate. Acetyl-CoA can act as acetyl donor in this activation only if trace amounts of adenine nucleotides and auxiliary enzymes are present. These allow formation of acetyl adenylate in acetate- and ATP-generating reactions.

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Year:  1974        PMID： 4365579      PMCID： PMC388369          DOI： 10.1073/pnas.71.5.1987

Source DB:  PubMed          Journal:  Proc Natl Acad Sci U S A        ISSN： 0027-8424            Impact factor:   11.205


  10 in total

1.  Acyl adenylates; an enzymatic mechanism of acetate activation.

Authors:  P BERG
Journal:  J Biol Chem       Date:  1956-10       Impact factor: 5.157

2.  Acetyl coenzyme a synthesis through pyrophosphoryl split of adenosine triphosphate.

Authors:  M E JONES; S BLACK; R M FLYNN; F LIPMANN
Journal:  Biochim Biophys Acta       Date:  1953 Sep-Oct

3.  The acetate activating enzyme system of heart muscle.

Authors:  H BEINERT; D E GREEN; P HELE; H HIFT; R W VON KORFF; C V RAMAKRISHNAN
Journal:  J Biol Chem       Date:  1953-07       Impact factor: 5.157

4.  [On the optical determination of citrate synthase and acetyl-coenzyme A].

Authors:  W Buckel; H Eggerer
Journal:  Biochem Z       Date:  1965-11-05

5.  S-acetyl phosphopantetheine: deacetyl citrate lyase S-acetyl transferase from Klebsiella aerogenes.

Authors:  M Singh; B Böttger; C Stewart; G C Brooks; P A Srere
Journal:  Biochem Biophys Res Commun       Date:  1973-07-02       Impact factor: 3.575

6.  Acetyl-CoA-dependent cleavage of citrate on inactivated citrate lyase.

Authors:  W Buckel; K Ziegert; H Eggerer
Journal:  Eur J Biochem       Date:  1973-08-17

7.  [Enzyme catalyzed reactivation of inactive citrate lyase].

Authors:  H Schmellenkamp; H Eggerer
Journal:  Hoppe Seylers Z Physiol Chem       Date:  1972-10

8.  [The action mechanism of citrate lyase from Klebsiella aerogenes].

Authors:  W Buckel; V Buschmeier; H Eggerer
Journal:  Hoppe Seylers Z Physiol Chem       Date:  1971-09

9.  Sub-units of citrate oxaloacetate-lyase.

Authors:  T J Bowen; M G Mortimer
Journal:  Eur J Biochem       Date:  1971-11-11

10.  The acyl-carrier protein of citrate lyase.

Authors:  P Dimroth; W Dittmar; G Walther; H Eggerer
Journal:  Eur J Biochem       Date:  1973-08-17
  10 in total
  9 in total

1.  Genetic organization of the citCDEF locus and identification of mae and clyR genes from Leuconostoc mesenteroides.

Authors:  S Bekal-Si Ali; C Diviès; H Prévost
Journal:  J Bacteriol       Date:  1999-07       Impact factor: 3.490

2.  Isolation of subunits of citrate lyase and characterization of their function in the enzyme complex.

Authors:  P Dimroth; H Eggerer
Journal:  Proc Natl Acad Sci U S A       Date:  1975-09       Impact factor: 11.205

3.  Energy-dependent inactivation of citrate lyase in Enterobacter aerogenes.

Authors:  H Kulla; G Gottschalk
Journal:  J Bacteriol       Date:  1977-12       Impact factor: 3.490

4.  Inactivation of citrate lyase from Rhodopseudomonas gelatinosa by a specific deacetylase and inhibition of this inactivation by L-(+1-glutamate.

Authors:  F Giffhorn; G Gottschalk
Journal:  J Bacteriol       Date:  1975-12       Impact factor: 3.490

5.  The citrate metabolic pathway in Leuconostoc mesenteroides: expression, amino acid synthesis, and alpha-ketocarboxylate transport.

Authors:  C Marty-Teysset; J S Lolkema; P Schmitt; C Diviès; W N Konings
Journal:  J Bacteriol       Date:  1996-11       Impact factor: 3.490

6.  Effect of growth conditions on the activation and inactivation of citrate lyase of Rhodopseudomonas gelatinosa.

Authors:  F Giffhorn; G Gottschalk
Journal:  J Bacteriol       Date:  1975-12       Impact factor: 3.490

7.  Purification of Leuconostoc mesenteroides citrate lyase and cloning and characterization of the citCDEFG gene cluster.

Authors:  S Bekal; J Van Beeumen; B Samyn; D Garmyn; S Henini; C Diviès; H Prévost
Journal:  J Bacteriol       Date:  1998-02       Impact factor: 3.490

8.  Citrate lyase from Streptococcus diacetilactis. Association with its acetylating enzyme.

Authors:  A Kümmel; G Behrens; G Gottschalk
Journal:  Arch Microbiol       Date:  1975       Impact factor: 2.552

9.  Structure of the prosthetic group of Klebsiella aerogenes citrate (pro-3S)-lyase.

Authors:  J B Robinson; M Singh; P A Srere
Journal:  Proc Natl Acad Sci U S A       Date:  1976-06       Impact factor: 11.205
  9 in total

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