| Literature DB >> 4364534 |
T B Strom, A J Sytkowski, C B Carpenter, J P Merrill.
Abstract
Cholinergic agonists have previously been shown to augment the ability of sensitized lymphocytes to injure cells bearing the sensitizing alleantigens. The cholinergic receptor of the attacking lymphocyte population has been studied with pharmacological manipulation of an in vitro system that quantitates the injury mediated by sensitized attacking cells upon target cells. The data reveal that muscarinic ligands are several orders of magnitude more potent than nicotinic agents in altering cytotoxicity.Entities:
Mesh：
Substances：
Year: 1974 PMID： 4364534 PMCID： PMC388221 DOI： 10.1073/pnas.71.4.1330
Source DB: PubMed Journal: Proc Natl Acad Sci U S A ISSN： 0027-8424 Impact factor: 11.205