Literature DB >> 4364362

Thyroid hormone action: in vitro demonstration of putative receptors in isolated nuclei and soluble nuclear extracts.

H H Samuels, J S Tsai, J Casanova.   

Abstract

Saturable binding activities for triiodothyronine were demonstrated in vitro with isolated nuclei and soluble nuclear extracts of rat liver, kidney, and cultured GH(1) cells. The binding activity can be extracted from nuclei in soluble form with no significant change in hormone affinity and has properties of a nonhistone protein.

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Year:  1974        PMID： 4364362     DOI： 10.1126/science.184.4142.1188

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  7 in total

Review 1.  Endogenous ligands for nuclear receptors: digging deeper.

Authors:  Michael Schupp; Mitchell A Lazar
Journal:  J Biol Chem       Date:  2010-10-18       Impact factor: 5.157

2.  Thyroid hormone binding by a component of mitochondrial membrane.

Authors:  K Sterling; P O Milch
Journal:  Proc Natl Acad Sci U S A       Date:  1975-08       Impact factor: 11.205

3.  Contributions of plasma triiodothyronine and local thyroxine monodeiodination to triiodothyronine to nuclear triiodothyronine receptor saturation in pituitary, liver, and kidney of hypothyroid rats. Further evidence relating saturation of pituitary nuclear triiodothyronine receptors and the acute inhibition of thyroid-stimulating hormone release.

Authors:  J E Silva; P R Larsen
Journal:  J Clin Invest       Date:  1978-05       Impact factor: 14.808

4.  Identification of differentially expressed thyroid hormone responsive genes from the brain of the Mexican Axolotl (Ambystoma mexicanum).

Authors:  P Huggins; C K Johnson; A Schoergendorfer; S Putta; A C Bathke; A J Stromberg; S R Voss
Journal:  Comp Biochem Physiol C Toxicol Pharmacol       Date:  2011-03-30       Impact factor: 3.228

Review 5.  Molecular aspects of thyroid hormone actions.

Authors:  Sheue-Yann Cheng; Jack L Leonard; Paul J Davis
Journal:  Endocr Rev       Date:  2010-01-05       Impact factor: 19.871

6.  Thyroid hormone action: in vitro characterization of solubilized nuclear receptors from rat liver and cultured GH1 cells.

Authors:  H H Samuels; J S Tsai; J Casanova; F Stanley
Journal:  J Clin Invest       Date:  1974-10       Impact factor: 14.808

Review 7.  Nuclear hormone receptor functions in keratinocyte and melanocyte homeostasis, epidermal carcinogenesis and melanomagenesis.

Authors:  Stephen Hyter; Arup K Indra
Journal:  FEBS Lett       Date:  2013-02-05       Impact factor: 4.124
  7 in total

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