Literature DB >> 4363967

High performance liquid chromatography of ceramides: application to analysis in human tissues and demonstration of ceramide excess in Farber's disease.

M Sugita, M Iwamori, J Evans, R H McCluer, J T Dulaney, H W Moser.   

Abstract

Conditions have been determined for the benzoylation of ceramides containing nonhydroxy and hydroxy fatty acids, and a high performance liquid chromatography system for the separation and measurement of these derivatives has been devised that is capable of good resolution and high sensitivity. These methods have been used to determine quantitatively the levels of ceramides in human tissues, and in serum and urine, and to demonstrate elevated amounts of ceramide in Farber's disease urine and tissues.

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Year:  1974        PMID： 4363967

Source DB:  PubMed          Journal:  J Lipid Res        ISSN： 0022-2275            Impact factor:   5.922


  14 in total

Review 1.  Basic findings and current developments in sphingolipidoses.

Authors:  H Pilz; R Heipertz; D Seidel
Journal:  Hum Genet       Date:  1979-03-12       Impact factor: 4.132

Review 2.  Current methods for the identification and quantitation of ceramides: an overview.

Authors:  A E Cremesti; A S Fischl
Journal:  Lipids       Date:  2000-09       Impact factor: 1.880

3.  A simple fluorogenic method for determination of acid ceramidase activity and diagnosis of Farber disease.

Authors:  Carmen Bedia; Luz Camacho; José Luís Abad; Gemma Fabriàs; Thierry Levade
Journal:  J Lipid Res       Date:  2010-09-24       Impact factor: 5.922

Review 4.  Fatty acid 2-Hydroxylation in mammalian sphingolipid biology.

Authors:  Hiroko Hama
Journal:  Biochim Biophys Acta       Date:  2009-12-21

5.  Acid Ceramidase Deficiency in Mice Results in a Broad Range of Central Nervous System Abnormalities.

Authors:  Jakub Sikora; Shaalee Dworski; E Ellen Jones; Mustafa A Kamani; Matthew C Micsenyi; Tomo Sawada; Pauline Le Faouder; Justine Bertrand-Michel; Aude Dupuy; Christopher K Dunn; Ingrid Cong Yang Xuan; Josefina Casas; Gemma Fabrias; David R Hampson; Thierry Levade; Richard R Drake; Jeffrey A Medin; Steven U Walkley
Journal:  Am J Pathol       Date:  2017-04       Impact factor: 4.307

6.  Sensitive analysis of ethanolamine- and serine-containing phosphoglycerides by high-performance liquid chromatography.

Authors:  F B Jungalwala; R J Turel; J E Evans; R H McCluer
Journal:  Biochem J       Date:  1975-03       Impact factor: 3.857

7.  Synthesis, NMR characterization and divergent biological actions of 2'-hydroxy-ceramide/dihydroceramide stereoisomers in MCF7 cells.

Authors:  Zdzislaw M Szulc; Aiping Bai; Jacek Bielawski; Nalini Mayroo; Doreen E Miller; Hanna Gracz; Yusuf A Hannun; Alicja Bielawska
Journal:  Bioorg Med Chem       Date:  2010-09-28       Impact factor: 3.641

8.  Simultaneous quantitation of ceramides and 1,2-diacylglycerol in tissues by Iatroscan thin-layer chromatography-flame-ionization detection.

Authors:  K Okumura; K Hayashi; I Morishima; K Murase; H Matsui; Y Toki; T Ito
Journal:  Lipids       Date:  1998-05       Impact factor: 1.880

9.  Myocardium of type 2 diabetic and obese patients is characterized by alterations in sphingolipid metabolic enzymes but not by accumulation of ceramide.

Authors:  Marcin Baranowski; Agnieszka Blachnio-Zabielska; Tomasz Hirnle; Dorota Harasiuk; Krzysztof Matlak; Malgorzata Knapp; Piotr Zabielski; Jan Gorski
Journal:  J Lipid Res       Date:  2010-01       Impact factor: 5.922

10.  Molecular species of sphingomyelin in sphingomyelinase-sensitive and sphingomyelinase-resistant pools of HL-60 cells.

Authors:  V Fitzgerald; M L Blank; F Snyder
Journal:  Lipids       Date:  1995-09       Impact factor: 1.880
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