Literature DB >> 436292

The preparation of 125I-labelled bile acid ligands for use in the radioimmunoassay of bile acids.

G J Beckett, J E Corrie, I W Percy-Robb.   

Abstract

A general method for the preparation of 125I-labelled bile acid-histamine or 125I-labelled bile acid-tyramine conjugates is presented. The method is simple, quick and produces ligands in good yield (30%). The characteristics of a radioimmunoassay for conjugated chenodeoxycholic acid, based on an 125I-labelled ligand prepared by the method, are also described. The assay produced values for fasting serum concentrations of conjugated chenodeoxycholic acid that agree well with previous data.

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Year:  1979        PMID： 436292     DOI： 10.1016/0009-8981(79)90255-9

Source DB:  PubMed          Journal:  Clin Chim Acta        ISSN： 0009-8981            Impact factor:   3.786


  4 in total

1.  Liver function in Edinburgh haemophiliacs: a five-year follow-up.

Authors:  M L Stirling; G J Beckett; I W Percy-Robb
Journal:  J Clin Pathol       Date:  1981-01       Impact factor: 3.411

2.  Clinical value of bile salt tests in anicteric liver disease.

Authors:  J G Douglas; G J Beckett; I A Nimmo; N D Finlayson; I W Percy-Robb
Journal:  Gut       Date:  1981-02       Impact factor: 23.059

3.  Variations in composition of dietary fats affect hepatic uptake and metabolism of chylomicron remnants.

Authors:  M S Lambert; K M Botham; P A Mayes
Journal:  Biochem J       Date:  1995-09-15       Impact factor: 3.857

4.  Are serum bile salt concentrations raised in hyperlipidaemia?

Authors:  G J Beckett; J G Douglas; N D Finlayson; I W Percy-Robb
Journal:  Gut       Date:  1980-03       Impact factor: 23.059
  4 in total

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