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Literature DB >> 4362448

Differentiation between the embryonic and tumour specific antigens on chemically induced rat tumours.

Abstract

The tumour specific antigens and tumour associated embryonic antigens expressed on chemically induced rat hepatomata and sarcomata have been shown to be different by means of blocking antibody studies. Serum from multiparous female rats contained blocking antibody which protected both tumour and embryo cells from the in vitro cytotoxic effect of lymph node cells from multiparous donors. These sera did not, however, block the cytotoxicity of lymph node cells from tumour immune rats for cells of the immunizing tumour. In addition, the tumour specific rejection antigens and embryonic antigens have been shown to have dissimilar locations in tumour cells.

Entities: CellLine Disease Species

Mesh：

Substances：
Antigens, Neoplasm

Year: 1974 PMID： 4362448 PMCID： PMC2009139 DOI： 10.1038/bjc.1974.1

Source DB: PubMed Journal: Br J Cancer ISSN： 0007-0920 Impact factor: 7.640

19 in total

1. Solubilization of tumour-specific antigen from plasma membrane of an aminoazo-dye-induced rat hepatoma.

Authors: R W Baldwin; D Glaves
Journal: Clin Exp Immunol Date: 1972-05 Impact factor: 4.330

2. Demonstration of cell-surface antigens on chemically induced tumors.

Authors: R W Baldwin; C R Barker; M J Embleton; D Glaves; M Moore; M V Pimm
Journal: Ann N Y Acad Sci Date: 1971-06-21 Impact factor: 5.691

3. Demonstration by colony inhibition methods of cellular and humoral immune reactions to tumour-specific antigens associated with aminoazo-dye-induced rat hepatomas.

Authors: R W Baldwin; M J Embleton
Journal: Int J Cancer Date: 1971-01-15 Impact factor: 7.396

4. Tumor immunity in hamsters immunized with fetal tissues.

Authors: J H Coggin; K R Ambrose; B B Bellomy; N G Anderson
Journal: J Immunol Date: 1971-08 Impact factor: 5.422

5. Isolation of membrane-associated tumour-specific antigen from an aminoazo-dye-induced rat hepatoma.

Authors: R W Baldwin; M Moore
Journal: Int J Cancer Date: 1969-11-15 Impact factor: 7.396

6. Fetal antigen capable of inducing transplantation immunity against SV40 hamster tumor cells.

Authors: J H Coggin; K R Ambrose; N G Anderson
Journal: J Immunol Date: 1970-08 Impact factor: 5.422

7. Enzymic removal and re-expression of a histocompatibility antigen, HL-A 2, at the surface of human peripheral lymphocytes ( 31 Cr-labeled cells-papain-puromycin-actinomycin D).

Authors: M J Turner; J L Strominger; A R Sanderson
Journal: Proc Natl Acad Sci U S A Date: 1972-01 Impact factor: 11.205

Differentiation between the embryonic and tumour specific antigens on chemically induced rat tumours.

1. Solubilization of tumour-specific antigen from plasma membrane of an aminoazo-dye-induced rat hepatoma.

2. Demonstration of cell-surface antigens on chemically induced tumors.

3. Demonstration by colony inhibition methods of cellular and humoral immune reactions to tumour-specific antigens associated with aminoazo-dye-induced rat hepatomas.

4. Tumor immunity in hamsters immunized with fetal tissues.

5. Isolation of membrane-associated tumour-specific antigen from an aminoazo-dye-induced rat hepatoma.

6. Fetal antigen capable of inducing transplantation immunity against SV40 hamster tumor cells.

7. Enzymic removal and re-expression of a histocompatibility antigen, HL-A 2, at the surface of human peripheral lymphocytes ( 31 Cr-labeled cells-papain-puromycin-actinomycin D).

8. Tumour-specific antigenicity of aminoazo-dye-induced rat hepatomas.

9. Transplantation antigen of mice: cellular localization of antigen determined by the H-2 locus.

10. Demonstration of tumour-specific humoral antibody against aminoazo dye-induced rat hepatomata.

1. The early detection of cancer.

2. Embryonic antigen expression on 2-acetylaminofluorene induced and spontaneously arising rat tumours.

3. Tumour-associated antigens reacting with cytotoxic antibodies in serum of hepatoma-bearing rats.