Literature DB >> 4358948

A filter assay for thymidylate synthetase using 5-fluoro-2'-deoxyuridylate as an active site titrant.

D V Santi, C S McHenry, E R Perriard.   

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Year:  1974        PMID： 4358948     DOI： 10.1021/bi00700a011

Source DB:  PubMed          Journal:  Biochemistry        ISSN： 0006-2960            Impact factor:   3.162


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  13 in total

1.  Functional evidence for active site location of tetrameric thymidylate synthase X at the interphase of three monomers.

Authors:  Damien Leduc; Sébastien Graziani; Gerard Lipowski; Christophe Marchand; Pierre Le Maréchal; Ursula Liebl; Hannu Myllykallio
Journal:  Proc Natl Acad Sci U S A       Date:  2004-04-27       Impact factor: 11.205

2.  Thymidylate synthetase purified to homogeneity from human leukemic cells.

Authors:  A Lockshin; R G Moran; P V Danenberg
Journal:  Proc Natl Acad Sci U S A       Date:  1979-02       Impact factor: 11.205

3.  Chemical shift imprint of intersubunit communication in a symmetric homodimer.

Authors:  Bradley T Falk; Paul J Sapienza; Andrew L Lee
Journal:  Proc Natl Acad Sci U S A       Date:  2016-07-27       Impact factor: 11.205

4.  Isolation and expression of the Pneumocystis carinii thymidylate synthase gene.

Authors:  U Edman; J C Edman; B Lundgren; D V Santi
Journal:  Proc Natl Acad Sci U S A       Date:  1989-09       Impact factor: 11.205

5.  The A+T-rich genome of Herpesvirus saimiri contains a highly conserved gene for thymidylate synthase.

Authors:  R W Honess; W Bodemer; K R Cameron; H H Niller; B Fleckenstein; R E Randall
Journal:  Proc Natl Acad Sci U S A       Date:  1986-06       Impact factor: 11.205

6.  Biochemical determinants of tumor sensitivity to 5-fluorouracil: ultrasensitive methods for the determination of 5-fluoro-2'-deoxyuridylate, 2'-deoxyuridylate, and thymidylate synthetase.

Authors:  R G Moran; C P Spears; C Heidelberger
Journal:  Proc Natl Acad Sci U S A       Date:  1979-03       Impact factor: 11.205

7.  Overproduction of a bifunctional thymidylate synthetase-dihydrofolate reductase and DNA amplification in methotrexate-resistant Leishmania tropica.

Authors:  J A Coderre; S M Beverley; R T Schimke; D V Santi
Journal:  Proc Natl Acad Sci U S A       Date:  1983-04       Impact factor: 11.205

8.  Resistance to multiple novel antifolates is mediated via defective drug transport resulting from clustered mutations in the reduced folate carrier gene in human leukaemia cell lines.

Authors:  Lilah Rothem; Ilan Ifergan; Yotam Kaufman; David G Priest; Gerrit Jansen; Yehuda G Assaraf
Journal:  Biochem J       Date:  2002-11-01       Impact factor: 3.857

9.  A radiochemical titrant for the determination of the operational molarity of solutions of acid proteinases.

Authors:  G B Irvine; D T Elmore
Journal:  Biochem J       Date:  1979-11-01       Impact factor: 3.857

10.  Association of RNA with thymidylate synthase from methotrexate-resistant Streptococcus faecium.

Authors:  K N Rao; R L Kisliuk
Journal:  Proc Natl Acad Sci U S A       Date:  1983-02       Impact factor: 11.205
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