| Literature DB >> 4351459 |
J R Stephenson, R E Wilsnack, S A Aaronson.
Abstract
A radioimmunoassay has been developed for detection of avian C-type virus (30,000 mol wt) group-specific (gs) antigen. The method is 10- to 1,000-fold more sensitive than immunological methods previously available. By the radioimmunoassay technique, normal chicken embryo cells, which have previously been classified as gs negative or weakly gs positive, contain clearly detectable amounts of gs antigen. The assay has been used to study the effect of chemical induction and superinfection by mammalian C-type viruses on the expression of avian gs antigen in mammalian cells nonproductively transformed by avian sarcoma viruses.Entities:
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Year: 1973 PMID: 4351459 PMCID: PMC355197
Source DB: PubMed Journal: J Virol ISSN: 0022-538X Impact factor: 5.103