Literature DB >> 435123

Biochemical, hematological and histological changes in a fulminant hepatic failure rat model for artificial liver assessment.

E Chirito, C Lister, T M Chang.   

Abstract

Galactosamine-induced fulminant hepatic failure rats have been used as a model for statistical assessment of liver support systems. The present study reports in detail the biochemical, hematological and histological changes in these animals. They have been used to study statistically the effects of ACAC charcoal hemoperfusion, cross-circulation and liver perfusion on long-term survival in fulminant hepatic failure.

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Year:  1979        PMID: 435123     DOI: 10.1111/j.1525-1594.1979.tb03804.x

Source DB:  PubMed          Journal:  Artif Organs        ISSN: 0160-564X            Impact factor:   3.094


  3 in total

1.  Fulminant hepatic failure and artificial liver support.

Authors:  A E Gimson; R Ede; S Braude; R D Hughes; P J Langley; R Williams
Journal:  Gastroenterol Jpn       Date:  1982-04

2.  Hepatosplanchnic haemodynamics and renal blood flow and function in rats with liver failure.

Authors:  P Javlé; J Yates; H G Kynaston; K F Parsons; S A Jenkins
Journal:  Gut       Date:  1998-08       Impact factor: 23.059

3.  A fulminant hepatic failure model in the rat: involvement of interleukin-1beta and tumor necrosis factor-alpha.

Authors:  M Shito; U J Balis; R G Tompkins; M L Yarmush; M Toner
Journal:  Dig Dis Sci       Date:  2001-08       Impact factor: 3.199

  3 in total

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