Literature DB >> 4349510

Octopamine-sensitive adenylate cyclse: evidence for a biological role of octopamine in nervous tissue.

J A Nathanson, P Greengard.   

Abstract

An adenylate cyclase that is activated specifically by very low concentrations of octopamine has been identified both in homogenates and in intact cells of the thoracic ganglia of an insect nervous system. This enzyme appears to be distinct from two other adenylate cyclases present in the same tissue, which are activated by dopamine and by 5-hydroxytryptamine, respectively. The data raise the possibility of a role of octopamine-sensitive adenylate cyclase in the physiology of synaptic transmission.

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Year:  1973        PMID: 4349510     DOI: 10.1126/science.180.4083.308

Source DB:  PubMed          Journal:  Science        ISSN: 0036-8075            Impact factor:   47.728


  21 in total

1.  Cloning and functional characterization of a novel dopamine receptor from Drosophila melanogaster.

Authors:  G Feng; F Hannan; V Reale; Y Y Hon; C T Kousky; P D Evans; L M Hall
Journal:  J Neurosci       Date:  1996-06-15       Impact factor: 6.167

2.  Adenosine 3',5'-monophosphate in snail (Helix pomatia) nervous system: analysis of dopamine receptors.

Authors:  N N Osborne
Journal:  Experientia       Date:  1977-07-15

3.  Octopamine receptors in the honey bee and locust nervous system: pharmacological similarities between homologous receptors of distantly related species.

Authors:  J Degen; M Gewecke; T Roeder
Journal:  Br J Pharmacol       Date:  2000-06       Impact factor: 8.739

4.  Electron-microscopic cytochemical study of cyclic nucleotide phosphodiesterase in rat brain.

Authors:  K Sugimura; A Mizutani
Journal:  Histochemistry       Date:  1978-03-02

5.  Characterization of octopamine-sensitive adenylate cyclase: elucidation of a class of potent and selective octopamine-2 receptor agonists with toxic effects in insects.

Authors:  J A Nathanson
Journal:  Proc Natl Acad Sci U S A       Date:  1985-01       Impact factor: 11.205

6.  Effect of halothane-nitrous oxide anaesthesia on the behaviour of 'sustained' and 'transient' visual cortical neurones.

Authors:  H Ikeda; M J Wright
Journal:  J Physiol       Date:  1974-03       Impact factor: 5.182

7.  Weak neuronal accumulation of octopamine in dopaminergic neurons of the rabbit retina.

Authors:  B Ehinger
Journal:  Experientia       Date:  1976

8.  Fluorometric determination of octopamine in tissue homogenates by high-performance liquid chromatography.

Authors:  L D Mell; D O Carpenter
Journal:  Neurochem Res       Date:  1980-10       Impact factor: 3.996

9.  The association of octopamine with specific neurones along lobster nerve trunks.

Authors:  P D Evans; E A Kravitz; B R Talamo; B G Wallace
Journal:  J Physiol       Date:  1976-10       Impact factor: 5.182

10.  Pharmacology of the octopamine receptor from locust central nervous tissue (OAR3).

Authors:  T Roeder
Journal:  Br J Pharmacol       Date:  1995-01       Impact factor: 8.739

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