Literature DB >> 434887

Reduction of insulin dose on changing diabetic children from standard to monocomponent insulins.

N K Griffin, M A Smith, J D Baum.   

Abstract

21 diabetic children requiring greater than 50 units of standard insulin daily were changed to a monocomponent insulin. During the 3 months before the change the insulin dose had risen significantly from a mean of 70 to a mean of 77 units daily. During the 3 months after the change the dose fell significantly to a mean of 53 units daily. This decrease in insulin requirement was associated with a general improvement in diabetic control. This was assessed clinically and measured in 10 children by an analysis of home urine tests and in 8 children by an analysis of 24-hour urine glucose excretion.

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Year:  1979        PMID: 434887      PMCID: PMC1545381          DOI: 10.1136/adc.54.2.123

Source DB:  PubMed          Journal:  Arch Dis Child        ISSN: 0003-9888            Impact factor:   3.791


  7 in total

1.  Hazards of monocomponent insulins.

Authors:  A W Logie; J M Stowers
Journal:  Br Med J       Date:  1976-04-10

2.  Clinical trial with monocomponent lente insulins. Preliminary report.

Authors:  B Bruni; M D'Alberto; M Osenda; C Ricci; G L Turco
Journal:  Diabetologia       Date:  1973-12       Impact factor: 10.122

3.  Immunogenicity of insulin.

Authors:  M A Root; R E Chance; J A Galloway
Journal:  Diabetes       Date:  1972       Impact factor: 9.461

4.  New forms of insulin.

Authors:  J A Galloway; M A Root
Journal:  Diabetes       Date:  1972       Impact factor: 9.461

5.  Clinical aspects of insulin--antigenicity.

Authors:  J Schlichtkrull; J Brange; A H Christiansen; O Hallund; L G Heding; K H Jorgensen
Journal:  Diabetes       Date:  1972       Impact factor: 9.461

6.  [The place of "monocomponent" insulins in diabetes mellitus therapy].

Authors:  A Teuscher
Journal:  Schweiz Med Wochenschr       Date:  1975-04-19

7.  Effect of "fractionated" insulins on total plasma insulin binding capacity and insulin requirements in severe diabetes.

Authors:  N W Oakley
Journal:  Lancet       Date:  1976-05-08       Impact factor: 79.321

  7 in total
  3 in total

1.  Hospital admission rates of diabetic children.

Authors:  J Hardie; K McPherson; J D Baum
Journal:  Diabetologia       Date:  1979-04       Impact factor: 10.122

2.  The effect of insulin antibodies on insulin dose and diabetic control.

Authors:  S Walford; S P Allison; W G Reeves
Journal:  Diabetologia       Date:  1982-02       Impact factor: 10.122

3.  Diabetic control in patients treated with once or twice-daily insulin injections, including a comparison of conventional beef and highly purified pork insulins.

Authors:  R S Gray; D Q Borsey; D M Fraser; A B Kurtz; S Rainbow; A F Smith; L J Duncan; B F Clarke
Journal:  Diabetologia       Date:  1981-09       Impact factor: 10.122

  3 in total

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