Literature DB >> 434834

Metabolic activation and hepatotoxicity. Effect of cysteine, N-acetylcysteine, and methionine on glutathione biosynthesis and bromobenzene toxicity in isolated rat hepatocytes.

H Thor, P Moldéus, S Orrenius.   

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Year:  1979        PMID: 434834     DOI: 10.1016/0003-9861(79)90109-7

Source DB:  PubMed          Journal:  Arch Biochem Biophys        ISSN: 0003-9861            Impact factor:   4.013


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  21 in total

1.  Hormone-mediated down-regulation of hepatic glutathione synthesis in the rat.

Authors:  S C Lu; J Kuhlenkamp; C Garcia-Ruiz; N Kaplowitz
Journal:  J Clin Invest       Date:  1991-07       Impact factor: 14.808

2.  The biosynthesis of taurine fromN-acetyl-L-cysteine and other precursorsin vivo and in rat hepatocytes.

Authors:  C J Waterfield; J A Timbrell
Journal:  Amino Acids       Date:  1996-06       Impact factor: 3.520

3.  Glutathione replenishment capacity is lower in isolated perivenous than in periportal hepatocytes.

Authors:  Y Kera; K E Penttilä; K O Lindros
Journal:  Biochem J       Date:  1988-09-01       Impact factor: 3.857

4.  Oxidant lung injury: intervention with sulfhydryl reagents.

Authors:  C E Patterson; J A Butler; F D Byrne; M L Rhodes
Journal:  Lung       Date:  1985       Impact factor: 2.584

5.  The role of acetylcysteine in clinical toxicology.

Authors:  R J Flanagan
Journal:  Med Toxicol       Date:  1987 Mar-Apr

Review 6.  Role of membrane transport in metabolism and function of glutathione in mammals.

Authors:  S Bannai; N Tateishi
Journal:  J Membr Biol       Date:  1986       Impact factor: 1.843

7.  The effect of cysteine oxidation on isolated hepatocytes.

Authors:  J Viña; G T Saez; D Wiggins; A F Roberts; R Hems; H A Krebs
Journal:  Biochem J       Date:  1983-04-15       Impact factor: 3.857

8.  The mechanism of bromobenzene-induced cytotoxicity studied with isolated hepatocytes.

Authors:  H Thor; S Orrenius
Journal:  Arch Toxicol       Date:  1980-03       Impact factor: 5.153

9.  Mechanism of the protective action of n-acetylcysteine and methionine against paracetamol toxicity in the hamster.

Authors:  S Pratt; C Ioannides
Journal:  Arch Toxicol       Date:  1985-08       Impact factor: 5.153

10.  Glutathione redox cycle is an important defense system of endothelial cells against chronic hyperoxia.

Authors:  N Suttorp; S Kästle; H Neuhof
Journal:  Lung       Date:  1991       Impact factor: 2.584

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