Literature DB >> 43477

Increase by alpha-adrenolytic drugs of acetylcholine release evoked by field stimulation of the guinea-pig ileum.

H Kilbinger, I Wessler.   

Abstract

The release of acetylcholine evoked by field stimulation of the guinea-pig ileum (3 Hz) is increased by yohimbine and tolazoline but not affected by phentolamine. It is proposed that yohimbine and tolazoline by blocking alpha-adrenoceptors of the cholinergic nerves abolish the inhibition caused by endogenous noradrenaline, and thus facilitate the output of acetylcholine.

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Year:  1979        PMID： 43477     DOI： 10.1007/bf00504758

Source DB:  PubMed          Journal:  Naunyn Schmiedebergs Arch Pharmacol        ISSN： 0028-1298            Impact factor:   3.000


  9 in total

1.  The effects of morphine on the release of noradrenaline from the cat isolated nictitating membrane and the guinea-pig ileum myenteric plexus-longitudinal muscle preparation.

Authors:  G Henderson; J Hughes; H W Kosterlitz
Journal:  Br J Pharmacol       Date:  1975-04       Impact factor: 8.739

2.  The pharmacology of benzyl-imidazoline (Priscol).

Authors:  R P AHLQUIST; R A HUGGINS; R A WOODBURY
Journal:  J Pharmacol Exp Ther       Date:  1947-03       Impact factor: 4.030

3.  A comparison of pre- and postsynaptic effects of alpha-adrenolytic drugs in the pulmonary artery of the rabbit.

Authors:  E Borowski; K Starke; H Ehrl; T Endo
Journal:  Neuroscience       Date:  1977       Impact factor: 3.590

4.  The effects of sympathetic nerve stimulation and guanethidine on parasympathetic neuroeffector transmission; the inhibition of acetylcholine release.

Authors:  E S Vizi; J Knoll
Journal:  J Pharm Pharmacol       Date:  1971-12       Impact factor: 3.765

5.  Gas chromatographic estimation of acetylcholine in the rabbit heart using a nitrogen selective detector.

Authors:  H Kilbinger
Journal:  J Neurochem       Date:  1973-08       Impact factor: 5.372

6.  Formation and release of acetylpyrrolidinecholine (N-methyl, N-acetoxyethylpyrrolidinium) as a false cholinergic transmitter in the myenteric plexus of the guinea-pig small intestine.

Authors:  H Kilbinger
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1977-01       Impact factor: 3.000

7.  Differentiation between pre- and postjunctional alpha-receptors in guinea pig ileum and rabbit aorta.

Authors:  J Wikberg
Journal:  Acta Physiol Scand       Date:  1978-07

8.  Pharmacological characterization of the presynaptic alpha-adrenoceptors regulating cholinergic activity in the guinea-pig ileum.

Authors:  G M Drew
Journal:  Br J Pharmacol       Date:  1978-10       Impact factor: 8.739

9.  The inhibitory action of noradrenaline and adrenaline on acetylcholine output by guinea-pig ileum longitudinal muscle strip.

Authors:  W D Paton; E S Vizi
Journal:  Br J Pharmacol       Date:  1969-01       Impact factor: 8.739
  9 in total
  11 in total

1.  Presynaptic effects of scopolamine, oxotremorine, noradrenaline and morphine on [3H]acetylcholine release from the myenteric plexus at different stimulation frequencies and calcium concentrations.

Authors:  I Wessler; V Eschenbruch; S Halim; H Kilbinger
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1987-06       Impact factor: 3.000

2.  Effect of alpha-adrenoceptor agonists and antagonists on cholinergic transmission in guinea-pig isolated atria.

Authors:  R E Loiacono; D F Story
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1986-09       Impact factor: 3.000

3.  Alpha- and beta-adrenoceptor-mediated responses of the guinea-pig ileum and the effects of neuronal uptake inhibition.

Authors:  K J Broadley; P F Grassby
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1985-12       Impact factor: 3.000

4.  Mediator release from isolated rat ileum in response to field stimulation.

Authors:  P Blandina; M Barattini; R Fantozzi; E Masini; S Brunelleschi; P F Mannaioni
Journal:  Agents Actions       Date:  1984-04

5.  Capsaicin-sensitive afferents activate a sympathetic intestinointestinal inhibitory reflex in dogs.

Authors:  M Mizutani; T Neya; S Nakayama
Journal:  J Physiol       Date:  1990-06       Impact factor: 5.182

6.  Presynaptic muscarinic and alpha-adrenoceptor-mediated regulation of GABA release from myenteric neurones of the guinea-pig small intestine.

Authors:  S Hashimoto; C Tanaka; K Taniyama
Journal:  Br J Pharmacol       Date:  1986-12       Impact factor: 8.739

7.  Subsensitivity of enteric cholinergic neurones to alpha 2-adrenoceptor agonists after chronic sympathetic denervation.

Authors:  M Marcoli; S Lecchini; F De Ponti; L D'Angelo; A Crema; G M Frigo
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1985-05       Impact factor: 3.000

8.  The effects of metoclopramide on acetylcholine release and on smooth muscle response in the isolated guinea-pig ileum.

Authors:  H Kilbinger; R Kruel; I Pfeuffer-Friederich; I Wessler
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1982-06       Impact factor: 3.000

9.  A submucosal mechanism for catecholamine-induced increases in fluid absorption in rabbit ileum in vitro.

Authors:  M A Ahsan; R J Naftalin; P M Smith
Journal:  J Physiol       Date:  1988-10       Impact factor: 5.182

10.  Effects of some alpha-adrenoceptor agonists and antagonists on the guinea-pig ileum.

Authors:  M Andréjak; Y Pommier; P Mouillé; H Schmitt
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1980-10       Impact factor: 3.000
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