Literature DB >> 4339394

Degradation of angiotensin II by plasmin.

G Dudek, Z S Latallo, J Prokopowicz, K Worowski.   

Abstract

1. Synthetic angiotensin II (Hypertensin, Ciba, Basel) was incubated with a water-insoluble preparation of plasmin (E.C. 3.4.4.14) and the resulting products analysed by paper chromatography and N-terminal amino-acid analysis.2. Only the N-terminal asparagine was split off from the peptide. This indicates that plasmin attacks the Asn-Arg but not the Arg-Val in angiotensin II molecule.

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Year:  1972        PMID: 4339394      PMCID: PMC1666177          DOI: 10.1111/j.1476-5381.1972.tb09576.x

Source DB:  PubMed          Journal:  Br J Pharmacol        ISSN: 0007-1188            Impact factor:   8.739


  12 in total

1.  A mammalian peptidase specific for the hydrolysis of N-terminal alpha-L-glutamyl and aspartyl residues.

Authors:  G G GLENNER; P J McMILLAN; J E FOLK
Journal:  Nature       Date:  1962-06-02       Impact factor: 49.962

2.  Partial purification and properties of a proteolytic enzyme of human serum.

Authors:  L F REMMERT; P P COHEN
Journal:  J Biol Chem       Date:  1949-11       Impact factor: 5.157

3.  Purification and properties of endopeptidase from rabbit red cells and its process of degradation of angiotensin.

Authors:  T Kokubu; H Akutsu; S Fujimoto; E Ueda; K Hiwada; Y Yamamura
Journal:  Biochim Biophys Acta       Date:  1969

4.  Unknown properties of the products of plasmin-degradation of fibrinogen and fibrin.

Authors:  K Buluk; M Malofiejew; M Czokalo
Journal:  Bull Acad Pol Sci Biol       Date:  1966

5.  Partial inactivation of angiotensin II by plasmin.

Authors:  J Prokopowicz; K Worowski; S Niewiarowski
Journal:  Thromb Diath Haemorrh       Date:  1969-02-28

6.  New enzymatic route for the inactivation of angiotensin.

Authors:  H Y Yang; E G Erdös; T S Chiang
Journal:  Nature       Date:  1968-06-29       Impact factor: 49.962

7.  Thin-layer chromatographic separation of DNS-amino acids.

Authors:  D Morse; B L Horecker
Journal:  Anal Biochem       Date:  1966-03       Impact factor: 3.365

8.  Fibrinolytic system in the dog with experimental renal (Goldblatt) hypertension.

Authors:  J Prokopowicz; K Worowski; A Poplawski; M Mysliwiec; S Niewiarowski
Journal:  Experientia       Date:  1967-03-15

9.  Angiotensinase with a high degree of specificity in plasma and red cells.

Authors:  P A KHAIRALLAH; F M BUMPUS; I H PAGE; R R SMEBY
Journal:  Science       Date:  1963-05-10       Impact factor: 47.728

10.  ANTIGENS AND ENZYMES MADE INSOLUBLE BY ENTRAPPING THEM INTO LATTICES OF SYNTHETIC POLYMERS.

Authors:  P BERNFELD; J WAN
Journal:  Science       Date:  1963-11-08       Impact factor: 47.728

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