Literature DB >> 4336227

Lack of significant oncogenicity of biological products in hamsters.

C B Cox, J Landon, M G Valerio, A Palmer, R L Kirschstein, S H Singer.   

Abstract

A variety of biological products which included live and inactivated viral vaccines, inactivated rickettsial and bacterial vaccines, toxoids, and a multiple bacterial antigen product did not appear to be oncogenic for newborn hamsters following a single subcutaneous inoculation. The incidence of spontaneous tumors was approximately 4.7%, and this figure was not significantly altered by the inoculation of any of the test materials.

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Year:  1972        PMID: 4336227      PMCID: PMC380416          DOI: 10.1128/am.23.4.675-678.1972

Source DB:  PubMed          Journal:  Appl Microbiol        ISSN: 0003-6919


  13 in total

1.  TESTS IN HAMSTERS FOR ONCOGENIC QUALITY OF ORDINARY VIRUSES INCLUDING ADENOVIRUS TYPE 7.

Authors:  A J GIRARDI; M R HILLEMAN; R E ZWICKEY
Journal:  Proc Soc Exp Biol Med       Date:  1964-04

2.  FURTHER TESTS IN HAMSTERS FOR ONCOGENIC QUALITY OF ORDINARY VIRUSES AND MYCOPLASMA, WITH CORRELATIVE REVIEW.

Authors:  A J GIRARDI; V M LARSON; M R HILLEMAN
Journal:  Proc Soc Exp Biol Med       Date:  1965-01

3.  TUMORS PRODUCED BY ADENOVIRUS 12 IN MASTOMYS AND MICE.

Authors:  A S RABSON; R L KIRSCHSTEIN; F J PAUL
Journal:  J Natl Cancer Inst       Date:  1964-01       Impact factor: 13.506

4.  A preliminary report concerning tumors observed in Syrian hamsters.

Authors:  H KIRKMAN
Journal:  Stanford Med Bull       Date:  1962-11

5.  Transplantable tumors of the Syrian (golden) hamster. I. Tumors of the alimentary tract, endocrine glands and melanomas.

Authors:  J G FORTNER; A G MAHY; G R SCHRODT
Journal:  Cancer Res       Date:  1961-07       Impact factor: 12.701

6.  Seven viruses isolated from the vervet monkey.

Authors:  H MALHERBE; R HARWIN
Journal:  Br J Exp Pathol       Date:  1957-10

7.  Spontaneous tumors including gastrointestinal neoplasms and malignant melanomas, in the Syrian hamster.

Authors:  J G FORTNER
Journal:  Cancer       Date:  1957 Nov-Dec       Impact factor: 6.860

8.  New viral agents recovered from tissue cultures of monkey kidney cells. III. Recovery of additional agents both from cultures of monkey tissues and directly from tissues and excreta.

Authors:  R N HULL; J R MINNER; C C MASCOLI
Journal:  Am J Hyg       Date:  1958-07

9.  The quest for human cancer viruses.

Authors:  J J TRENTIN; Y YABE; G TAYLOR
Journal:  Science       Date:  1962-09-14       Impact factor: 47.728

10.  Sarcomas in hamsters after injection with Rous chicken tumor material.

Authors:  C G AHLSTROM; N FORSBY
Journal:  J Exp Med       Date:  1962-04-01       Impact factor: 14.307

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