| Literature DB >> 433600 |
E Nordenfelt, E Helgstrand, B Oberg.
Abstract
Evidence available indicates that the so-called Dane particles are the hepatitis virus. A DNA polymerase is associated with the core of these particles. The probability that this is the viral DNA polymerase offers the possibility of preventing hepatitis B multiplication by selective inhibition of this enzyme. This investigation reports that trisodium phosphonoformate (PFA) at low concentrations but not phosphonoacetate acid (PAA) inhitits Dane particle associated DNA polymerase.Entities:
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Year: 1979 PMID： 433600 DOI： 10.1111/j.1699-0463.1979.tb02406.x
Source DB: PubMed Journal: Acta Pathol Microbiol Scand B ISSN： 0105-0656