Literature DB >> 4335298

Beclomethasone dipropionate: a new steroid aerosol for the treatment of allergic asthma.

H M Brown, G Storey, W H George.   

Abstract

Beclomethasone dipropionate was used in pressurized aerosols for the treatment of 60 cases of chronic allergic asthma for up to 15 months. Twenty-eight out of 37 cases were transferred to this treatment after being dependent on oral steroids for up to 16 years. Nineteen out of 23 other asthmatics not dependent on steroids were also completely controlled. No biochemical evidence of adrenal suppression was found. Steroid withdrawal symptoms were often a problem, suggesting absence of systemic absorption. The precise mode of action and metabolic fate of this corticosteroid are not yet known.

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Year:  1972        PMID: 4335298      PMCID: PMC1787564          DOI: 10.1136/bmj.1.5800.585

Source DB:  PubMed          Journal:  Br Med J        ISSN: 0007-1447


  17 in total

1.  Asthma, allergy and steroids.

Authors:  H M BROWN
Journal:  Br J Clin Pract       Date:  1961-12

2.  Treatment of chronic asthma with prednisolone; significance of eosinophils in the sputum.

Authors:  H M BROWN
Journal:  Lancet       Date:  1958-12-13       Impact factor: 79.321

3.  Hydrocortisone hemisuccinate by inhalation in children with asthma.

Authors:  J M SMITH
Journal:  Lancet       Date:  1958-12-13       Impact factor: 79.321

4.  Local treatment of bronchial asthma with hydrocortisone powder.

Authors:  H HERXHEIMER; M K McALLEN; D A WILLIAMS
Journal:  Br Med J       Date:  1958-09-27

5.  Bronchial asthma and chronic bronchitis treated with hydrocortisone acetate inhalations.

Authors:  W H HELM; F HEYWORTH
Journal:  Br Med J       Date:  1958-09-27

6.  Chronic asthma treated with powder inhalations of hydrocortisone and prednisolone.

Authors:  W BROCKBANK; C D PENGELLY
Journal:  Lancet       Date:  1958-01-25       Impact factor: 79.321

7.  Chronic asthma treated with aerosol hydrocortisone.

Authors:  H BREBNER; W BROCKBANK; C D PENGELLY
Journal:  Lancet       Date:  1956-10-20       Impact factor: 79.321

8.  Administration of cortisone by the aerosol method in the treatment of bronchial asthma.

Authors:  M L GELFAND
Journal:  N Engl J Med       Date:  1951-08-23       Impact factor: 91.245

9.  Some aspects of clinical allergy.

Authors:  H M Brown
Journal:  Br J Clin Pract       Date:  1970-12

10.  Inhalational vs oral steroid therapy in childhood asthma.

Authors:  L P Kravis; H I Lecks
Journal:  Am J Dis Child       Date:  1966-04
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  69 in total

1.  Effects of corticosteroids in acute severe asthma.

Authors:  N C Barnes
Journal:  Thorax       Date:  1992-08       Impact factor: 9.139

2.  Intranasal beclomethasone: wonder drug or hazard.

Authors: 
Journal:  Br Med J       Date:  1976-12-25

3.  The childhood asthma epidemic.

Authors:  G Russell
Journal:  Thorax       Date:  2006-04       Impact factor: 9.139

4.  Drugs for asthma.

Authors:  Peter J Barnes
Journal:  Br J Pharmacol       Date:  2006-01       Impact factor: 8.739

Review 5.  Very high dose inhaled corticosteroids: panacea or poison?

Authors:  G Russell
Journal:  Arch Dis Child       Date:  2006-10       Impact factor: 3.791

6.  Chest diseases-epitomes of progress: corticosteroid aerosols in the treatment of asthma.

Authors:  J E Hodgkin
Journal:  West J Med       Date:  1977-10

7.  A self management plan in the treatment of adult asthma.

Authors:  R Beasley; M Cushley; S T Holgate
Journal:  Thorax       Date:  1989-03       Impact factor: 9.139

8.  Recovery of adrenal function after substitution of beclomethasone dipropionate for oral corticosteroids.

Authors:  D J Maberly; G J Gibson; A G Butler
Journal:  Br Med J       Date:  1973-03-31

9.  Beclomethasone dipropionate aerosol in treatment of perennial allergic rhinitis in children.

Authors:  S C Shore; E G Weinberg
Journal:  Arch Dis Child       Date:  1977-06       Impact factor: 3.791

10.  New perspectives in allergic asthma.

Authors:  S O Freedman
Journal:  Can Med Assoc J       Date:  1976-02-21       Impact factor: 8.262

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