Literature DB >> 4333994

Intravascular degranulation of neutrophils: an important factor in inflammation?

H R Schumacher, C A Agudelo.   

Abstract

Polymorphonuclear leukocytes are degranulated in the lumens of vessels in synovial membrane in humans with various types of inflammatory arthritis and in dogs with synovitis induced by urate crystals. This degranulation, accompanied by the release of lysosomal enzymes and vasoactive materials, may be an important part of the mechanism resulting in vascular injury.

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Year:  1972        PMID： 4333994     DOI： 10.1126/science.175.4026.1139

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  4 in total

1.  Periprosthetic osteolysis: characterizing the innate immune response to titanium wear-particles.

Authors:  Christine A St Pierre; Melvin Chan; Yoichiro Iwakura; David C Ayers; Evelyn A Kurt-Jones; Robert W Finberg
Journal:  J Orthop Res       Date:  2010-11       Impact factor: 3.494

2.  Colonic epithelial cells and polymorphonuclear leukocytes in ulcerative colitis. An electron-microscopic study.

Authors:  W O Dobbins
Journal:  Am J Dig Dis       Date:  1975-03

3.  Neutrophil-mediated endothelial injury in vitro mechanisms of cell detachment.

Authors:  J M Harlan; P D Killen; L A Harker; G E Striker; D G Wright
Journal:  J Clin Invest       Date:  1981-12       Impact factor: 14.808

4.  The glomerular mesangium. 3. Acute immune mesangial injury: a new model of glomerulonephritis.

Authors:  S M Mauer; D E Sutherland; R J Howard; A J Fish; J S Najarian; A F Michael
Journal:  J Exp Med       Date:  1973-03-01       Impact factor: 14.307
  4 in total

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