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Literature DB >> 4333979

Activity of ribosomes containing 5S RNA with a chemically modified 3'-terminus.

Abstract

Ribosomes containing 5S RNA in which the 3'-terminus has been modified chemically, either by periodate oxidation or by conversion of the terminal ribose to a morpholine derivative, are fully as active in peptidebond formation and polypeptide synthesis as those ribosomes with unmodified 5S RNA. These results exclude models for protein synthesis in which peptidyl-5S RNA is formed as an intermediate.

Entities: Chemical

Mesh：

Substances：

Year: 1972 PMID： 4333979 PMCID： PMC426458 DOI： 10.1073/pnas.69.2.363

Source DB: PubMed Journal: Proc Natl Acad Sci U S A ISSN： 0027-8424 Impact factor: 11.205

5 in total

1. NUCLEOTIDE SEQUENCE ANALYSIS OF POLYRIBONUCLEOTIDES BY MEANS OF PERIODATE OXIDATION FOLLOWED BY CLEAVAGE WITH AN AMINE.

Authors: H C NEU; L A HEPPEL
Journal: J Biol Chem Date: 1964-09 Impact factor: 5.157

2. The reaction of methylamine with periodate-oxidized adenosine 5'-phosphate.

Authors: J X KHYM
Journal: Biochemistry Date: 1963 Mar-Apr Impact factor: 3.162

3. Inactivation and reactivation of ribosomal subunits: the peptidyl transferase activity of the 50 s subunit of Escherihia coli.

Authors: R Miskin; A Zamir; D Elson
Journal: J Mol Biol Date: 1970-12-14 Impact factor: 5.469

4. Role of 5S RNA in the functions of 50S ribosomal subunits.

Authors: V A Erdmann; S Fahnestock; K Higo; M Nomura
Journal: Proc Natl Acad Sci U S A Date: 1971-12 Impact factor: 11.205

5. A model for protein synthesis involving the intermediate formation of peptidyl-5S RNA.

Authors: I D Raacke
Journal: Proc Natl Acad Sci U S A Date: 1971-10 Impact factor: 11.205

5 in total

7 in total

6. Poly(rC) binding protein 2 binds to stem-loop IV of the poliovirus RNA 5' noncoding region: identification by automated liquid chromatography-tandem mass spectrometry.

Authors: L B Blyn; K M Swiderek; O Richards; D C Stahl; B L Semler; E Ehrenfeld
Journal: Proc Natl Acad Sci U S A Date: 1996-10-01 Impact factor: 11.205

7. Surface topography of the Bacillus stearothermophilus ribosome.

Authors: H M Miller; S M Friedman
Journal: Mol Gen Genet Date: 1976-03-30

7 in total

Activity of ribosomes containing 5S RNA with a chemically modified 3'-terminus.

1. NUCLEOTIDE SEQUENCE ANALYSIS OF POLYRIBONUCLEOTIDES BY MEANS OF PERIODATE OXIDATION FOLLOWED BY CLEAVAGE WITH AN AMINE.

2. The reaction of methylamine with periodate-oxidized adenosine 5'-phosphate.

3. Inactivation and reactivation of ribosomal subunits: the peptidyl transferase activity of the 50 s subunit of Escherihia coli.

4. Role of 5S RNA in the functions of 50S ribosomal subunits.

5. A model for protein synthesis involving the intermediate formation of peptidyl-5S RNA.

1. An RNA molecule copurifies with RNase P activity from Xenopus laevis oocytes.

2. Differential utilization of poly(rC) binding protein 2 in translation directed by picornavirus IRES elements.

3. Affinity chromatography with an immobilized RNA enzyme.

4. Functional group recognition at the aminoacylation and editing sites of E. coli valyl-tRNA synthetase.

5. Expression of ribosomal protein genes as analyzed by bacteriophage Mu-induced mutations.

6. Poly(rC) binding protein 2 binds to stem-loop IV of the poliovirus RNA 5' noncoding region: identification by automated liquid chromatography-tandem mass spectrometry.

7. Surface topography of the Bacillus stearothermophilus ribosome.