Literature DB >> 433384

Schistosoma mansoni: activity responses in vitro to praziquantel.

C J Chavasse, M C Brown, D R Bell.   

Abstract

The effects of praziquantel, a novel antischistosomal compound, on the activity of adult Schistosoma mansoni (Liverpool strain) in vitro were investigated. Worm activity was modified at all concentrations of praziquantel. High concentrations (above 0.5 microgram/ml) produced rapid paralysis, whilst low concentrations of praziquantel stimulated worm activity. It is concluded that such activity modification could lead to worm displacement in vivo.

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Year:  1979        PMID： 433384     DOI： 10.1007/bf01951341

Source DB:  PubMed          Journal:  Z Parasitenkd        ISSN： 0044-3255


  8 in total

1.  A comparison of the susceptibility to praziquantel of Schistosoma haematobium, S. japonicum, S. mansoni, S. intercalatum and S. mattheei im hamsters.

Authors:  G Webbe; C James
Journal:  Z Parasitenkd       Date:  1977-07-21

2.  A multichannel ultrasonic activity monitor for in-vitro screening of antischistosomal drugs.

Authors:  M C Brown; D F Norman; D R Bell; C J Chavasse
Journal:  Med Biol Eng Comput       Date:  1978-07       Impact factor: 2.602

3.  Evoked-response averaging techniques used to clarify the effect of drugs on the in vitro activity of schistosomes.

Authors:  M C Brown; C J Chavasse; D F Norman; D R Bell
Journal:  Med Biol Eng Comput       Date:  1978-09       Impact factor: 2.602

4.  Experimental chemotherapy of schistosomiasis mansoni. XIII. Activity of praziquantel, an isoquinoline-pyrazino derivative, on mice, hamsters and Cebus monkeys.

Authors:  J Pellegrino; F F Lima-Costa; M A Carlos; R T Mello
Journal:  Z Parasitenkd       Date:  1977-07-21

5.  Short-term effects of oxamniquine on the activity in vitro of Schistosoma mansoni.

Authors:  C J Chavasse; M C Brown; D R Bell
Journal:  Ann Trop Med Parasitol       Date:  1978-06

6.  The susceptibility to praziquantel of Schistosoma haematobium in the baboon (Papio anubis) and of S. japonicum in the vervet monkey (Cercopithecus aethiops).

Authors:  C James; G Webbe; G S Nelson
Journal:  Z Parasitenkd       Date:  1977-07-21

7.  Praziquantel, a new board-spectrum antischistosomal agent.

Authors:  R Gönnert; P Andrews
Journal:  Z Parasitenkd       Date:  1977-07-21

8.  A benzodiazepine derivative and praziquantel: effects on musculature of Schistosoma mansoni and Schistosoma japonicum.

Authors:  R Pax; J L Bennett; R Fetterer
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1978-10       Impact factor: 3.000
  8 in total
  9 in total

1.  Reversible paralysis of Schistosoma mansoni by forchlorfenuron, a phenylurea cytokinin that affects septins.

Authors:  Ana E Zeraik; Vitold E Galkin; Gabriel Rinaldi; Richard C Garratt; Michael J Smout; Alex Loukas; Victoria H Mann; Ana P U Araujo; Ricardo DeMarco; Paul J Brindley
Journal:  Int J Parasitol       Date:  2014-04-21       Impact factor: 3.981

2.  Time course of the effect of praziquantel on Schistosoma mansoni attachment in vitro: comparison with its effects on worm length and motility.

Authors:  S P da Silva; F Noël
Journal:  Parasitol Res       Date:  1995       Impact factor: 2.289

3.  Further studies on mefloquine and praziquantel alone or interaction of both drugs against Schistosoma japonicum in vitro.

Authors:  Shu-hua Xiao; Jian Xue; Hao-bing Zhang
Journal:  Parasitol Res       Date:  2011-08-19       Impact factor: 2.289

4.  Praziquantel treatment of muscle Taenia solium cysticercosis. 4. Reversible in vitro effect.

Authors:  C Garcia-Dominguez; D Correa; M T Rabiela; A Flisser
Journal:  Parasitol Res       Date:  1991       Impact factor: 2.289

5.  Effect of praziquantel on adult Echinococcus granulosus in vitro: scanning electron microscopy.

Authors:  G A Conder; A A Marchiondo; F L Andersen
Journal:  Z Parasitenkd       Date:  1981

6.  In Vitro Cestocidal Activity of Thymol on Mesocestoides corti Tetrathyridia and Adult Worms.

Authors:  M Maggiore; M C Elissondo
Journal:  Interdiscip Perspect Infect Dis       Date:  2014-09-03

Review 7.  Pharmacological and immunological effects of praziquantel against Schistosoma japonicum: a scoping review of experimental studies.

Authors:  Shu-Hua Xiao; Jun Sun; Ming-Gang Chen
Journal:  Infect Dis Poverty       Date:  2018-02-07       Impact factor: 4.520

8.  In vitro and in vivo activity of R- and S- praziquantel enantiomers and the main human metabolite trans-4-hydroxy-praziquantel against Schistosoma haematobium.

Authors:  Jana Kovač; Mireille Vargas; Jennifer Keiser
Journal:  Parasit Vectors       Date:  2017-08-01       Impact factor: 3.876

9.  Is arachidonic acid an endoschistosomicide?

Authors:  Violette Said Hanna; Azza Gawish; Marwa Abou El-Dahab; Hatem Tallima; Rashika El Ridi
Journal:  J Adv Res       Date:  2018-01-10       Impact factor: 10.479
  9 in total

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