| Literature DB >> 4332626 |
H R Brunner, J D Kirshman, J E Sealey, J H Laragh.
Abstract
Antibody to angiotensin 11, or a specific peptide competitive inhibitor of angiolensin II, was used to investigate the role of the renin-angiotensin system in two types of renal hypertension in rats. The data indicate that angiotensin II is in fact critically involved in the pathogenesis of the form of renal hypertension in which one renal artery is clamped and the contralateral kidney is left in place, but that it probably plays no significant role in the maintenance of experimental renal hypertension in which the opposite kidney has been removed.Entities:
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Year: 1971 PMID： 4332626 DOI： 10.1126/science.174.4016.1344
Source DB: PubMed Journal: Science ISSN： 0036-8075 Impact factor: 47.728