| Literature DB >> 4332148 |
S Oroszlan, M Hatanaka, R V Gilden, R J Huebner.
Abstract
Inhibition of the ribonucleic acid (RNA)- and deoxyribonucleic acid (DNA)-dependent DNA polymerase activities of mammalian C-type viruses was obtained with sera from rats bearing murine leukemia virus-induced transplant tumors. Polymerase activities of nonmammalian (viper) C-type virus and murine mammary tumor virus were not inhibited by such sera nor by serum from a rat immunized with the DNA polymerase of feline leukemia virus purified by isoelectric focusing. The latter serum appeared to inhibit preferentially the DNA-dependent DNA polymerase activity of mammalian C-type viruses showing no inhibition of RNA-dependent DNA synthesis.Entities:
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Year: 1971 PMID: 4332148 PMCID: PMC376267
Source DB: PubMed Journal: J Virol ISSN: 0022-538X Impact factor: 5.103