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Literature DB >> 4329563

Relationship between virus-induced cellular deoxyribonucleic acid synthesis and transformation by simian virus 40.

Abstract

The fraction of cells in a confluent 3T3 cell monolayer induced by simian virus 40 infection to replicate deoxyribonucleic acid and divide corresponds to those cells which eventually become transformed. Virus-induced cells were partially separated from noninduced cells by sedimentation through Ficoll gradients. Three- to eightfold higher transformation frequencies were obtained with those cells that began to synthesize cellular deoxyribonucleic acid and divide shortly after simian virus 40 infection as compared to noninduced cells.

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Year: 1971 PMID： 4329563 PMCID： PMC356146

Source DB: PubMed Journal: J Virol ISSN： 0022-538X Impact factor: 5.103

13 in total

10. Deoxyribonucleic acid replication in simian virus 40-infected cells. 3. Comparison of simian virus 40 lytic infection in three different monkey kidney cell lines.

Authors: E Ritzi; A J Levine
Journal: J Virol Date: 1970-06 Impact factor: 5.103

6 in total

Relationship between virus-induced cellular deoxyribonucleic acid synthesis and transformation by simian virus 40.

1. Absence of a cell membrane alteration function in non-transforming mutants of polyoma virus.

2. DNA replication in SV40 infected cells. I. Analysis of replicating SV40 DNA.

3. Viral DNA in polyoma- and SV40-transformed cell lines.

4. The integrated state of viral DNA in SV40-transformed cells.

5. Stimulation of DNA synthesis in mouse cell line 3T3 by Simian virus 40.

6. An assay for cellular transformation by SV40.

7. The use of ficoll gradient centrifugation to produce synchronous mouse lymphoma cells.

8. A simple method for concentration of cells in the DNA synthetic period of the mitotic cycle.

9. Animal cells: noncorrelation of length of G1 phase with size after mitosis.

10. Deoxyribonucleic acid replication in simian virus 40-infected cells. 3. Comparison of simian virus 40 lytic infection in three different monkey kidney cell lines.

1. Evidence for an "early early" vaccinia virus-induced protein which causes a density change of infected L-M cells.

2. Induction of human cell DNA synthesis by herpes simplex virus type 2.

3. Transformation of primary hamster embryo fibroblasts by type 2 simplex virus: evidence for a "hit and run" mechanism.

4. Sedimentation changes of L cells in a density gradient early after infection with vaccinia virus.

5. Induction of cellular DNA synthesis by the nondefective Adenovirus 2-Simian virus 40 hybrid viruses.

6. Reinitiation within one cell cycle of the deoxyribonucleic acid synthesis induced by simian virus 40.