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Literature DB >> 4328412

Effect of inactivation by hydroxylamine on early functions of poliovirus.

K Borgert, K Koschel, H Täuber, E Wecker.

Abstract

Evidence is presented that poliovirus particles with a single lethal hit by hydroxylamine do not induce in host cells either inhibition of cellular protein synthesis or viral ribonucleic acid (RNA) replication. The RNA of these viruses is not replicated even if the cells are simultaneously infected with both active and inactivated viruses. The damaged viral RNA seems to have lost both its template function and its function in the translation of normal viral proteins.

Entities: Chemical Species

Mesh：

Substances：

Year: 1971 PMID： 4328412 PMCID： PMC356207

Source DB: PubMed Journal: J Virol ISSN： 0022-538X Impact factor: 5.103

27 in total

1. BEHAVIOR OF VIRUS-SPECIFIC ACTIVITIES IN TISSUE CULTURES INFECTED WITH MYXOVIRUSES AFTER CHEMICAL CHANGES OF THE VIRAL RIBONUCLEIC ACID.

Authors: C SCHOLTISSEK; R ROTT
Journal: Virology Date: 1964-02 Impact factor: 3.616

2. REPLICATION OF POLIOVIRUS RNA INDUCED BY HETEROLOGOUS VIRUS.

Authors: C E CORDS; J J HOLLAND
Journal: Proc Natl Acad Sci U S A Date: 1964-06 Impact factor: 11.205

3. GENOMIC MASKING PRODUCED BY DOUBLE-INFECTION OF HELA CELLS WITH HETEROTYPIC POLIOVIRUSES.

Authors: E WECKER; G LEDERHILGER
Journal: Proc Natl Acad Sci U S A Date: 1964-09 Impact factor: 11.205

4. NUCLEIC ACID AND PROTEIN SYNTHESIS DURING POLIOVIRUS INFECTION OF HUMAN CELLS.

Authors: J J HOLLAND; J A PETERSON
Journal: J Mol Biol Date: 1964-04 Impact factor: 5.469

5. STUDIES ON THE MULTIPLICATION OF A MEMBER OF THE COLUMBIA SK GROUP (ME VIRUS) IN L CELLS. IV. ROLE OF "EARLY PROTEINS" IN VIRUS INDUCED METABOLIC CHANGES.

Authors: D W VERWOERD; P HAUSEN
Journal: Virology Date: 1963-12 Impact factor: 3.616

1. Proteolysis of the p220 component of the cap-binding protein complex is not sufficient for complete inhibition of host cell protein synthesis after poliovirus infection.

Authors: A M Bonneau; N Sonenberg
Journal: J Virol Date: 1987-04 Impact factor: 5.103

2. Inactivation by hydroxylamine, O-methylhydroxylamine and N-methylhydroxylamine of representative myxoviruses and paramyxoviruses. Brief report.

Authors: G E Newlin; R H Bussell
Journal: Arch Gesamte Virusforsch Date: 1972

3. Restriction of translation of capped mRNA in vitro as a model for poliovirus-induced inhibition of host cell protein synthesis: relationship to p220 cleavage.

Authors: R E Lloyd; H G Jense; E Ehrenfeld
Journal: J Virol Date: 1987-08 Impact factor: 5.103

4. Poliovirus infection and poly(A) sequences of cytoplasmic cellular RNA.

Authors: K Koschel
Journal: J Virol Date: 1974-05 Impact factor: 5.103

4 in total

Effect of inactivation by hydroxylamine on early functions of poliovirus.

1. BEHAVIOR OF VIRUS-SPECIFIC ACTIVITIES IN TISSUE CULTURES INFECTED WITH MYXOVIRUSES AFTER CHEMICAL CHANGES OF THE VIRAL RIBONUCLEIC ACID.

2. REPLICATION OF POLIOVIRUS RNA INDUCED BY HETEROLOGOUS VIRUS.

3. GENOMIC MASKING PRODUCED BY DOUBLE-INFECTION OF HELA CELLS WITH HETEROTYPIC POLIOVIRUSES.

4. NUCLEIC ACID AND PROTEIN SYNTHESIS DURING POLIOVIRUS INFECTION OF HUMAN CELLS.

5. STUDIES ON THE MULTIPLICATION OF A MEMBER OF THE COLUMBIA SK GROUP (ME VIRUS) IN L CELLS. IV. ROLE OF "EARLY PROTEINS" IN VIRUS INDUCED METABOLIC CHANGES.

6. RNA synthesis in poliovirus-infected cells.

7. Alterations in HeLa cell metabolism resulting from poliovirus infection.

8. Polypeptide cleavages in the formation of poliovirus proteins.

9. Polyacrylamide gel electrophoresis of influenza virus RNA.

10. The effect of infection with fowl plague virus on protein synthesis in chick embryo cells.

1. Proteolysis of the p220 component of the cap-binding protein complex is not sufficient for complete inhibition of host cell protein synthesis after poliovirus infection.

2. Inactivation by hydroxylamine, O-methylhydroxylamine and N-methylhydroxylamine of representative myxoviruses and paramyxoviruses. Brief report.

3. Restriction of translation of capped mRNA in vitro as a model for poliovirus-induced inhibition of host cell protein synthesis: relationship to p220 cleavage.

4. Poliovirus infection and poly(A) sequences of cytoplasmic cellular RNA.