Literature DB >> 4327001

Serologic evidence that a herpes-type virus is the etiologic agent of heterophile-positive infectious mononucleosis.

B Hampar, K C Hsu, L M Martos, J L Walker.   

Abstract

The antibody activity against herpes-type virus (HTV) of heterophile-positive infectious mononucleosis sera and "normal" sera from humans was determined with immunoferritin. The antiviral activity of the mononucleosis sera was associated with the IgM antibodies, while the antiviral activity of the "normal" human sera was associated with the IgG antibodies. It was concluded from these findings that the appearance of antibodies to herpes-type virus in heterophile-positive sera represents a primary immunogenic exposure to this virus, or to a serologically related virus. This conclusion, in turn, suggests that herpes-type virus or a serologically related virus is the etiologic agent of heterophile-positive mononucleosis.

Entities:  

Mesh：

Substances：

Year:  1971        PMID： 4327001      PMCID： PMC389205          DOI： 10.1073/pnas.68.7.1407

Source DB:  PubMed          Journal:  Proc Natl Acad Sci U S A        ISSN： 0027-8424            Impact factor:   11.205


  19 in total

1.  Studies on EB virus of Burkitt's lymphoblasts.

Authors:  A Weinberg; Y Becker
Journal:  Virology       Date:  1969-10       Impact factor: 3.616

Review 2.  Antibody heterogeneity and serological reactions.

Authors:  R M Pike
Journal:  Bacteriol Rev       Date:  1967-06

3.  Examination of virus-gamma-M antibody complexes by electron microscopy. I. Configuration of gamma-M antibodies and mode of attachment to antigen.

Authors:  S E Svehag; B Bloth
Journal:  Virology       Date:  1967-04       Impact factor: 3.616

4.  Heterogeneity in the properties of 7 S and 19S rabbit-neutralizing antibodies to herpes simplex virus.

Authors:  B Hampar; A L Notkins; M Mage; M A Keehn
Journal:  J Immunol       Date:  1968-03       Impact factor: 5.422

5.  Infectious mononucleosis: complement-fixing antibodies to herpes-like virus associated with Burkitt lymphoma.

Authors:  P Gerber; D Hamre; R A Moy; E N Rosenblum
Journal:  Science       Date:  1968-07-12       Impact factor: 47.728

6.  Infectious mononucleosis. Clinical manifestations in relation to EB virus antibodies.

Authors:  J C Niederman; R W McCollum; G Henle; W Henle
Journal:  JAMA       Date:  1968-01-15       Impact factor: 56.272

7.  Radioimmunoelectrophoretic study of rabbit anti-protein antibodies during the primary response.

Authors:  M J Freeman; A B Stavitsky
Journal:  J Immunol       Date:  1965-12       Impact factor: 5.422

8.  Relation of Burkitt's tumor-associated herpes-ytpe virus to infectious mononucleosis.

Authors:  G Henle; W Henle; V Diehl
Journal:  Proc Natl Acad Sci U S A       Date:  1968-01       Impact factor: 11.205

9.  The coating reaction of the herpes-type virus isolated from malignant tissues with an antibody present in sera.

Authors:  S A Mayyasi; G Schidlovsky; L M Bulfone; F T Buscheck
Journal:  Cancer Res       Date:  1967-11       Impact factor: 12.701

10.  Herpes simplex virus products in productive and abortive infection. 3. Differentiation of infectious virus derived from nucleus and cytoplasm with respect to stability and size.

Authors:  S B Spring; B Roizman
Journal:  J Virol       Date:  1968-10       Impact factor: 5.103
View more
  9 in total

1.  Improved Epstein-Barr virus immunoglobulin M antibody test.

Authors:  J H Joncas; M Granger-Julien; F Gervais
Journal:  J Clin Microbiol       Date:  1975-02       Impact factor: 5.948

2.  Infectious mononucleosis and mononucleosis syndromes.

Authors:  M Fiala; D C Heiner; J A Turner; B Rosenbloom; L B Guze
Journal:  West J Med       Date:  1977-06

3.  Measurement of heterophil antibody and antibodies to EB viral capsid antigen IgG and IgM in suspected cases of infectious mononucleosis.

Authors:  J M Blake; J M Edwards; W Fletcher; D A McSwiggan; M S Pereira
Journal:  J Clin Pathol       Date:  1976-09       Impact factor: 3.411

4.  Persistence of a repressed Epstein-Barr virus genome in Burkitt lymphoma cells made resistant to 5-bromodeoxyuridine.

Authors:  B Hampar; J G Derge; L M Martos; J L Walker
Journal:  Proc Natl Acad Sci U S A       Date:  1971-12       Impact factor: 11.205

5.  Failure to detect heterophile antigens in Epstein-Barr virus-infected cells and to demonstrate interaction of heterophile antibodies with Epstein-Barr virus.

Authors:  W Henle; G Henle; J Hewetson; G Rocchi; J Leikola
Journal:  Clin Exp Immunol       Date:  1974-06       Impact factor: 4.330

6.  Studies on the diagnostic value of an immunofluorescence test for EB virus-specific IgM.

Authors:  J M Edwards; D A McSwiggan
Journal:  J Clin Pathol       Date:  1974-08       Impact factor: 3.411

7.  IgM antibodies specific for Epstein-Barr virus in infectious mononucleosis without heterophil antibodies.

Authors:  J Nikoskelainen; J Leikola; E Klemola
Journal:  Br Med J       Date:  1974-10-12

8.  Studies of human myasthenia gravis: electrophysiological and ultrastructural evidence compatible with antibody attachment to acetylcholine receptor complex.

Authors:  J E Rash; E X Albuquerque; C S Hudson; R F Mayer; J R Satterfield
Journal:  Proc Natl Acad Sci U S A       Date:  1976-12       Impact factor: 11.205

Review 9.  Commentary. EB virus, infectious mononucleosis, and cancer: the closing of the web.

Authors:  A S Evans
Journal:  Yale J Biol Med       Date:  1974
  9 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.