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Literature DB >> 4325000

Double-stranded poliovirus RNA inhibits initiation of protein synthesis by reticulocyte lysates.

Abstract

Infection of HeLa cells with poliovirus results in an inhibition of host-cell protein synthesis. Cytoplasmic extracts from infected cells contian an activity that inhibits initiation of protein synthesis in vitro by rabbit reticulocyte lysates. This inhibitory activity has been purified and characterized, and is shown to reside in poliovirus double-stranded RNA. The intact double-stranded molecule is not essential for inhibitory activity.

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Year: 1971 PMID： 4325000 PMCID： PMC389116 DOI： 10.1073/pnas.68.5.1075

Source DB: PubMed Journal: Proc Natl Acad Sci U S A ISSN： 0027-8424 Impact factor: 11.205

11 in total

1. POLYRIBOSOMES IN NORMAL AND POLIOVIRUS-INFECTED HELA CELLS AND THEIR RELATIONSHIP TO MESSENGER-RNA.

Authors: S Penman; K Scherrer; Y Becker; J E Darnell
Journal: Proc Natl Acad Sci U S A Date: 1963-05 Impact factor: 11.205

2. Cytoplasm from poliovirus-infected HeLa cells inhibits cell-free haemoglobin synthesis.

Authors: T Hunt; E Ehrenfeld
Journal: Nat New Biol Date: 1971-03-17

3. Soluble RNA polymerase complex from poliovirus-infected HeLa cells.

Authors: E Ehrenfeld; J V Maizel; D F Summers
Journal: Virology Date: 1970-04 Impact factor: 3.616

4. Purification and characterization of poliovirus-induced infectious double-stranded ribonucleic acid.

Authors: J M Bishop; G Koch
Journal: J Biol Chem Date: 1967-04-25 Impact factor: 5.157

5. Purification and properties of poliovirus double-stranded ribonucleic acid.

Authors: D Baltimore
Journal: J Mol Biol Date: 1966-07 Impact factor: 5.469

6. Evidence for virus-specific noncapsid proteins in poliovirus-infected HeLa cells.

Authors: D F Summers; J V Maizel; J E Darnell
Journal: Proc Natl Acad Sci U S A Date: 1965-08 Impact factor: 11.205

7. Characterization of ribonuclease-resistant RNA from poliovirus-infected HeLa cells.

Authors: J M Bishop; D F Summers; L Levintow
Journal: Proc Natl Acad Sci U S A Date: 1965-10 Impact factor: 11.205

8. Interferon stimulated by double stranded RNA.

Authors: T C Merigan
Journal: Nature Date: 1970-10-17 Impact factor: 49.962

9. Control of haemoglobin synthesis: distribution of ribosomes on the messenger RNA for alpha and beta chains.

Authors: T Hunt; T Hunter; A Munro
Journal: J Mol Biol Date: 1968-08-28 Impact factor: 5.469

10. Effects on host cell metabolism following synchronous infection with poliovirus.

Authors: S Penman; D Summers
Journal: Virology Date: 1965-12 Impact factor: 3.616

62 in total

1. Ability of formyl-methionyl-tRNA to initiate globin synthesis in the presence of double-stranded RNA or in the absence of hemin.

Authors: F Cahn; M Lubin
Journal: Mol Biol Rep Date: 1975-03 Impact factor: 2.316

2. Proteins synthesized by Semliki Forest virus and its 16 temperature-sensitive mutants.

Authors: S Keränen; L Kääriäinen
Journal: J Virol Date: 1975-08 Impact factor: 5.103

3. Interferon activity produced by translation of human interferon messenger RNA in cell-free ribosomal systems and in Xenopus oöcytes.

Authors: F H Reynolds; E Premkumar; P M Pitha
Journal: Proc Natl Acad Sci U S A Date: 1975-12 Impact factor: 11.205

4. Rhinovirus multistranded RNA: dependence of the replicative form on the presence of actinomycin D.

Authors: M R Macnaughton; J A Cooper; N J Dimmock
Journal: J Virol Date: 1976-06 Impact factor: 5.103

5. Association of a cyclic AMP-dependent protein kinase with a purified translational inhibitor isolated from hemin-deficient rabbit reticulocyte lysates.

Authors: D H Levin; R S Ranu; V Ernst; M A Fifer; L M London
Journal: Proc Natl Acad Sci U S A Date: 1975-12 Impact factor: 11.205

6. Poliovirus-induced infectious double-stranded RNA: Effect of RNA-degrading enzymes.

Authors: R Mittelstaedt; H Oppermann; G Koch
Journal: Arch Virol Date: 1975 Impact factor: 2.574

7. Interferon-induced inhibition of protein synthesis in L-cell extracts: an ATP-dependent step in the activation of an inhibitor by double-stranded RNA.

Authors: W K Roberts; M J Clemens; I M Kerr
Journal: Proc Natl Acad Sci U S A Date: 1976-09 Impact factor: 11.205

8. Degradation of the interferon-induced 68,000-M(r) protein kinase by poliovirus requires RNA.

Authors: T L Black; G N Barber; M G Katze
Journal: J Virol Date: 1993-02 Impact factor: 5.103

9. Induction of c-Ha-ras gene expression by double-stranded RNA and interferon requirement.

Authors: A Maran; I D Goldberg; B M Steinberg
Journal: Mol Cell Biol Date: 1990-08 Impact factor: 4.272

10. Double-stranded RNA as an inhibitor of protein synthesis and as a substrate for a nuclease in extracts of Krebs II ascites cells.

Authors: H D Robertson; M B Mathews
Journal: Proc Natl Acad Sci U S A Date: 1973-01 Impact factor: 11.205