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Literature DB >> 4323225

Fine structure of an oat cell carcinoma of the lung associated with ectopic ACTH syndrome.

Abstract

Electron-microscopic examination of an oat-cell carcinoma associated with the ectopic ACTH syndrome demonstrated characteristic cytoplasmic granules of 60-240 nm. diameter, consisting of a dense central core separated by a clear halo from an outer investing membrane. Comparison with previously examined non-secretory oat-cell carcinomas showed the granules to be more numerous in the present case. They are considered to represent secretory activity in the tumour.

Entities: Disease

Mesh：

Substances：

Year: 1970 PMID： 4323225 PMCID： PMC2008727 DOI： 10.1038/bjc.1970.90

Source DB: PubMed Journal: Br J Cancer ISSN： 0007-0920 Impact factor: 7.640

7 in total

1. Indirect analysis of corticosteroids. I. The determination of 17-hydroxycorticosteroids.

Authors: J I APPLEBY; G GIBSON; J K NORYMBERSKI; R D STUBBS
Journal: Biochem J Date: 1955-07 Impact factor: 3.857

2. A simple fluorimetric method for the estimation of free 11-hydroxycorticoids in human plasma.

Authors: D MATTINGLY
Journal: J Clin Pathol Date: 1962-07 Impact factor: 3.411

3. Effects of aminoglutethimide in a case of ectopic ACTH syndrome. Influence on steroid metabolism.

Authors: M McMillan; M N Maisey
Journal: Acta Endocrinol (Copenh) Date: 1970-08

4. Pathology of 'nonendocrine' tumors associated with Cushing's syndrome.

Authors: J G Azzopardi; E D Williams
Journal: Cancer Date: 1968-08 Impact factor: 6.860

5. Ultrastructural evidence of secretory differentiation in a malignant pleural mesothelioma.

Authors: R A Echevarria; V M Arean
Journal: Cancer Date: 1968-08 Impact factor: 6.860

Review 6. The cytochemistry and ultrastructure of polypeptide hormone-producing cells of the APUD series and the embryologic, physiologic and pathologic implications of the concept.

Authors: A G Pearse
Journal: J Histochem Cytochem Date: 1969-05 Impact factor: 2.479

7. Fine structural evidence for hormone secretion by a human thymic tumour.

Authors: R F Macadam; J M Vetters
Journal: J Clin Pathol Date: 1969-07 Impact factor: 3.411

7 in total

4 in total

Fine structure of an oat cell carcinoma of the lung associated with ectopic ACTH syndrome.

1. Indirect analysis of corticosteroids. I. The determination of 17-hydroxycorticosteroids.

2. A simple fluorimetric method for the estimation of free 11-hydroxycorticoids in human plasma.

3. Effects of aminoglutethimide in a case of ectopic ACTH syndrome. Influence on steroid metabolism.

4. Pathology of 'nonendocrine' tumors associated with Cushing's syndrome.

5. Ultrastructural evidence of secretory differentiation in a malignant pleural mesothelioma.

Review 6. The cytochemistry and ultrastructure of polypeptide hormone-producing cells of the APUD series and the embryologic, physiologic and pathologic implications of the concept.

7. Fine structural evidence for hormone secretion by a human thymic tumour.

1. Neurocristopathy, neuroendocrine pathology and the APUD concept.

2. AZD8055 inhibits ACTH secretion in a case of bilateral ACTH-secreting pheochromocytoma.

3. Ectopic ACTH syndrome: clinicopathological correlations.

Review 4. Ectopic production of hormones by tumours. Pathological aspects of the para-endocrine syndrome.