Literature DB >> 4322872

Virus-specific deoxyribonucleic acid in simian virus 40-exposed hamster cells: correlation with S and T antigens.

A S Levine, M N Oxman, P H Henry, M J Levin, G T Diamandopoulos, J F Enders.   

Abstract

Several homologous hamster embryonic cell lines, transformed in association with simian virus (SV) 40 infection, were examined for the presence of deoxyribonucleic acid (DNA) complementary to SV40 ribonucleic acid (RNA) made in vitro. The methods employed permitted the detection of 10(-5) mug of viral DNA in 100 mug of cellular DNA, corresponding to one-fifth of an SV40 DNA molecule per cell. Those lines which contained both the SV40 surface (S) and tumor (T) antigens also contained DNA complementary to SV40 RNA synthesized in vitro. In contrast, neither of two lines which contained S, but not T, antigen contained detectable DNA complementary to SV40 RNA. These findings suggest that the production of S antigen does not depend upon the persistence of SV40 DNA in transformed cells.

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Year:  1970        PMID： 4322872      PMCID： PMC376109     

Source DB:  PubMed          Journal:  J Virol        ISSN： 0022-538X            Impact factor:   5.103


  26 in total

1.  Virus-specific nucleic acids in SV40-exposed hamster embryo cell lines: correlation with S and T antigens.

Authors:  M J Levin; M N Oxman; G T Diamandopoulos; A S Levine; P H Henry; J F Enders
Journal:  Proc Natl Acad Sci U S A       Date:  1969-02       Impact factor: 11.205

2.  Viral DNA in polyoma- and SV40-transformed cell lines.

Authors:  H Westphal; R Dulbecco
Journal:  Proc Natl Acad Sci U S A       Date:  1968-04       Impact factor: 11.205

3.  Characterization of the simian virus 40-specific RNA in virus-yielding and transformed cells.

Authors:  Y Aloni; E Winocour; L Sachs
Journal:  J Mol Biol       Date:  1968-02-14       Impact factor: 5.469

4.  Development of S and T antigens and oncogenicity in hamster embryonic cell lines exposed to SV40.

Authors:  G T Diamandopoulos; S S Tevethia; F Rapp; J F Enders
Journal:  Virology       Date:  1968-02       Impact factor: 3.616

5.  Nucleic acid homology studies of SV 40 virus-transformed and normal hamster cells.

Authors:  P R Reich; P H Black; S M Weissman
Journal:  Proc Natl Acad Sci U S A       Date:  1966-07       Impact factor: 11.205

6.  The integrated state of viral DNA in SV40-transformed cells.

Authors:  J Sambrook; H Westphal; P R Srinivasan; R Dulbecco
Journal:  Proc Natl Acad Sci U S A       Date:  1968-08       Impact factor: 11.205

7.  Development in hamsters of antibodies against surface antigens present in cells transformed by papovavirus SV40.

Authors:  S S Tevethia; F Rapp
Journal:  J Immunol       Date:  1968-02       Impact factor: 5.422

8.  Use of immunofluorescence for detection of specific membrane antigen in simian virus 40-infected nontransformed cells.

Authors:  T E Kluchareva; K L Shachanina; S Belova; V Chibisova; G I Deichman
Journal:  J Natl Cancer Inst       Date:  1967-11       Impact factor: 13.506

9.  Repeated sequences in DNA. Hundreds of thousands of copies of DNA sequences have been incorporated into the genomes of higher organisms.

Authors:  R J Britten; D E Kohne
Journal:  Science       Date:  1968-08-09       Impact factor: 47.728

10.  A quantitative assay for DNA-RNA hybrids with DNA immobilized on a membrane.

Authors:  D Gillespie; S Spiegelman
Journal:  J Mol Biol       Date:  1965-07       Impact factor: 5.469
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  17 in total

1.  Simian virus 40 DNA replication, transcription, and antigen induction during infection with two adenovirus 2-SV40 hybrids that contain the entire SV40 genome.

Authors:  S E Siegel; C T Patch; A M Lewis; A S Levine
Journal:  J Virol       Date:  1975-07       Impact factor: 5.103

2.  Expression and thermal stability of simian virus 40 tumor-specific transplantation antigen and tumor antigen in wild type- and tsA mutant-transformed cells.

Authors:  J L Anderson; C Chang; P T Mora; R G Martin
Journal:  J Virol       Date:  1977-02       Impact factor: 5.103

3.  Lack of sequence homology between the 70S RNA of various RNA tumor viruses and the DNA of simian virus 40 or polyoma virus.

Authors:  R E Gallagher; A S Levine; D H Gillespie; R C Gallo
Journal:  J Virol       Date:  1973-06       Impact factor: 5.103

4.  Virus deoxyribonucleic acid sequences in subdiploid and subtetraploid revertants of polyoma-transformed cells.

Authors:  M Shani; Z Rabinowitz; L Sachs
Journal:  J Virol       Date:  1972-09       Impact factor: 5.103

5.  Quantitative in vitro measurement of simian virus 40 tumor-specific antigens.

Authors:  P W Wright; L W Law
Journal:  Proc Natl Acad Sci U S A       Date:  1971-05       Impact factor: 11.205

Review 6.  The tumor antigens and the early functions of polyoma virus.

Authors:  H Türler
Journal:  Mol Cell Biochem       Date:  1980-09-15       Impact factor: 3.396

7.  Fate of infecting simian virus 40-deoxyribonucleic acid in nonpermissive cells: integration into host deoxyribonucleic acid.

Authors:  C J Collins; G Sauer
Journal:  J Virol       Date:  1972-09       Impact factor: 5.103

8.  Demonstration of infectious deoxyribonucleic acid in transformed cells. I. Recovery of simian virus 40 from yielder and nonyielder transformed cells.

Authors:  V A Boyd; J S Butel
Journal:  J Virol       Date:  1972-09       Impact factor: 5.103

9.  Evidence for a transcription-control region of Simian virus 40 in the adenovirus 2--Simian virus 40 hybrid, Ad2+ND 1 .

Authors:  C T Patch; A M Lewis; A S Levine
Journal:  Proc Natl Acad Sci U S A       Date:  1972-11       Impact factor: 11.205

10.  Interaction of polyoma and mouse DNAs. IV. Time course and extent of integration of polyoma DNA into mouse DNA during lytic infection.

Authors:  H Türler
Journal:  J Virol       Date:  1977-08       Impact factor: 5.103
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