Literature DB >> 4322081

Adenovirus type 2-simian virus 40 hybrid population: evidence for a hybrid deoxyribonucleic acid molecule and the absence of adenovirus-encapsidated circular simian virus 40 deoxyribonucleic acid.

C S Crumpacker, M J Levin, W H Wiese, W P Rowe, A M Lewis.   

Abstract

The deoxyribonucleic acid (DNA) from the adenovirus-encapsidated particles of the adenovirus type 2 (Ad2)-simian virus 40 (SV40) hybrid population plaque variant (Ad2(++) HEY), known to yield SV40 virus with high efficiency, was studied by equilibrium density centrifugation followed by ribonucleic acid-DNA hybridization employing virus-specific complementary ribonucleic acids synthesized in vitro. These techniques establish linkage between the Ad2 and SV40 components in the adenovirus-encapsidated particles of this population. The linkage is alkali-resistant and presumably covalent; thus, the Ad2 DNA and SV40 DNA are present in a hybrid molecule. Velocity centrifugation studies in alkaline sucrose gradients eliminated the possibility that supercoiled circular SV40 DNA is present in the adenovirus capsids. The DNA obtained from the adenovirus-encapsidated particles of the Ad2(++) HEY population appears to consist of nonhybrid Ad2 DNA and Ad2-SV40 hybrid DNA molecules.

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Year:  1970        PMID： 4322081      PMCID： PMC376196     

Source DB:  PubMed          Journal:  J Virol        ISSN： 0022-538X            Impact factor:   5.103


  20 in total

1.  THE PURIFICATION OF SIMIAN VIRUS 40.

Authors:  P H BLACK; E M CRAWFORD; L V CRAWFORD
Journal:  Virology       Date:  1964-11       Impact factor: 3.616

2.  THE NUCLEIC ACID OF SIMIAN VIRUS 40.

Authors:  L V CRAWFORD; P H BLACK
Journal:  Virology       Date:  1964-11       Impact factor: 3.616

3.  BIOLOGIC CHARACTERISTICS OF A CONTINUOUS KIDNEY CELL LINE DERIVED FROM THE AFRICAN GREEN MONKEY.

Authors:  H E HOPPS; B C BERNHEIM; A NISALAK; J H TJIO; J E SMADEL
Journal:  J Immunol       Date:  1963-09       Impact factor: 5.422

4.  A study of the conditions and mechanism of the diphenylamine reaction for the colorimetric estimation of deoxyribonucleic acid.

Authors:  K BURTON
Journal:  Biochem J       Date:  1956-02       Impact factor: 3.857

5.  Virus-specific deoxyribonucleic acid in simian virus 40-exposed hamster cells: correlation with S and T antigens.

Authors:  A S Levine; M N Oxman; P H Henry; M J Levin; G T Diamandopoulos; J F Enders
Journal:  J Virol       Date:  1970-08       Impact factor: 5.103

6.  Virus-specific nucleic acids in SV40-exposed hamster embryo cell lines: correlation with S and T antigens.

Authors:  M J Levin; M N Oxman; G T Diamandopoulos; A S Levine; P H Henry; J F Enders
Journal:  Proc Natl Acad Sci U S A       Date:  1969-02       Impact factor: 11.205

7.  Occurrence of adenovirus-SV40 hybrids among monkey kidney cell adapted strains of adenovirus.

Authors:  A M Lewis; S G Baum; K O Prigge; W P Rowe
Journal:  Proc Soc Exp Biol Med       Date:  1966-05

8.  The process of infection with bacteriophage phi-X174 VII. Ultracentrifugal analysis of the replicative form.

Authors:  A Burton; R L Sinsheimer
Journal:  J Mol Biol       Date:  1965-12       Impact factor: 5.469

9.  Studies of adenovirus-SV40 hybrid viruses. IV. An adenovirus type 2 strain carrying the infectious SV40 genome.

Authors:  A M Lewis; K O Prigge; W P Rowe
Journal:  Proc Natl Acad Sci U S A       Date:  1966-03       Impact factor: 11.205

10.  Isolation of two plaque variants from the adenovirus type 2-simian virus 40 hybrid population which differ in their efficiency in yielding simian virus 40.

Authors:  A M Lewis; W P Rowe
Journal:  J Virol       Date:  1970-04       Impact factor: 5.103
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  6 in total

1.  Simian virus 40 DNA replication, transcription, and antigen induction during infection with two adenovirus 2-SV40 hybrids that contain the entire SV40 genome.

Authors:  S E Siegel; C T Patch; A M Lewis; A S Levine
Journal:  J Virol       Date:  1975-07       Impact factor: 5.103

2.  Palindromic adenovirus type 5-simian virus 40 hybrid.

Authors:  Y Gluzman; K Van Doren
Journal:  J Virol       Date:  1983-01       Impact factor: 5.103

3.  Indiscriminate recombination in simian virus 40-infected monkey cells.

Authors:  E Winocour; I Keshet
Journal:  Proc Natl Acad Sci U S A       Date:  1980-08       Impact factor: 11.205

4.  A colinear map relating the simian virus 40 (SV40) DNA segments of six adenovirus-SV40 hybrids to the DNA fragments produced by restriction endonuclease cleavage of SV40 DNA.

Authors:  P Lebowitz; T J Kelly; D Nathans; T N Lee; A M Lewis
Journal:  Proc Natl Acad Sci U S A       Date:  1974-02       Impact factor: 11.205

5.  Control of simian virus 40 gene expression in adenovirus-simian virus 40 hybrid viruses. Synthesis of hybrid adenovirus 2-simian virus 40 RNA molecules in cells infected with a nondefective adenovirus 2-simian virus 40 hybrid virus.

Authors:  M N Oxman; M J Levin; A M Lewis
Journal:  J Virol       Date:  1974-02       Impact factor: 5.103

6.  Use of nondefective adenovirus-simian virus 40 hybrids for mapping the simian virus 40 genome.

Authors:  T J Kelly; A M Lewis
Journal:  J Virol       Date:  1973-09       Impact factor: 5.103
  6 in total

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