Literature DB >> 43211

Injectable non-occlusive chemical contraception in the male-I.

M Misro, S K Guha, H Singh, S Mahajan, A R Ray, P Vasudevan.   

Abstract

A new contraceptive technique has been proposed and tested. The method uses a novel polymer which when injected into the vas deferens, lowers the pH sufficiently kill the spermatozoa passing through. The polymer itself does not degrade in the process but can be flushed out to regain fertility. Experiments carried out on rats demonstrate the efficacy of the technique so as to have non-surgical, non-occlusive and reversible male contraception.

Entities:  

Keywords:  Animals, Laboratory; Clinical Research; Contraception; Contraception Research; Contraceptive Agents; Contraceptive Agents, Male; Family Planning; In Vitro; Male Contraception; Male Sterilization; Research Methodology; Reversibility; Reversible Sterilization; Spermicidal Contraceptive Agents; Sterilization Reversal; Sterilization, Sexual

Mesh:

Substances:

Year:  1979        PMID: 43211     DOI: 10.1016/0010-7824(79)90052-0

Source DB:  PubMed          Journal:  Contraception        ISSN: 0010-7824            Impact factor:   3.375


  8 in total

Review 1.  RISUG: an intravasal injectable male contraceptive.

Authors:  N K Lohiya; I Alam; M Hussain; S R Khan; A S Ansari
Journal:  Indian J Med Res       Date:  2014-11       Impact factor: 2.375

2.  Reversibility of Vasalgel™ male contraceptive in a rabbit model.

Authors:  Donald Waller; David Bolick; Elaine Lissner; Christopher Premanandan; Gary Gamerman
Journal:  Basic Clin Androl       Date:  2017-04-05

Review 3.  The future of male contraception: a fertile ground.

Authors:  Iyad Khourdaji; Jacqueline Zillioux; Kevin Eisenfrats; Daniel Foley; Ryan Smith
Journal:  Transl Androl Urol       Date:  2018-05

4.  Can the evolution of male contraception lead to a revolution? Review of the current state of knowledge.

Authors:  Mikołaj Frankiewicz; Wojciech Połom; Marcin Matuszewski
Journal:  Cent European J Urol       Date:  2017-12-29

5.  Smart RISUG: a potential new contraceptive and its magnetic field-mediated sperm interaction.

Authors:  Rakhi K Jha; Pradeep K Jha; Sujoy K Guha
Journal:  Int J Nanomedicine       Date:  2009-04-01

6.  Azoospermia in rabbits following an intravas injection of Vasalgel ™.

Authors:  Donald Waller; David Bolick; Elaine Lissner; Christopher Premanandan; Gary Gamerman
Journal:  Basic Clin Androl       Date:  2016-03-30

7.  The contraceptive efficacy of intravas injection of Vasalgel™ for adult male rhesus monkeys.

Authors:  Angela Colagross-Schouten; Marie-Josee Lemoy; Rebekah I Keesler; Elaine Lissner; Catherine A VandeVoort
Journal:  Basic Clin Androl       Date:  2017-02-07

8.  RISUG® as a male contraceptive: journey from bench to bedside.

Authors:  Barkha Khilwani; Ayesha Badar; Abdul S Ansari; Nirmal K Lohiya
Journal:  Basic Clin Androl       Date:  2020-02-13
  8 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.