Literature DB >> 4319940

Tumorigenic effect of thioacetamide in Swiss strain mice.

S V Gothoskar, G V Talwalkar, S V Bhide.   

Abstract

Male and female Swiss strain mice were put on a 0.03% thioacetamide diet at the age of 2 months. Control mice were kept on a stock diet. Control and treated mice were killed at the ages of 6, 9, 13 and 17 months. Progressive morphological, histological and biochemical alterations in the liver and tumour tissue of the treated mice were studied. In the 17-month-old group, 12 out of 13 treated mice developed hepatomas.

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Year:  1970        PMID: 4319940      PMCID: PMC2008597          DOI: 10.1038/bjc.1970.60

Source DB:  PubMed          Journal:  Br J Cancer        ISSN: 0007-0920            Impact factor:   7.640


  6 in total

1.  Histological studies of liver cirrhosis in white rats by thioacetamide feeding.

Authors:  H MIYAZAKI; A WADA; H TAKAYANAGI
Journal:  Gan       Date:  1956-12

2.  A microchemical determination of desoxyribonucleic acid.

Authors:  G CERIOTTI
Journal:  J Biol Chem       Date:  1952-09       Impact factor: 5.157

3.  Protein measurement with the Folin phenol reagent.

Authors:  O H LOWRY; N J ROSEBROUGH; A L FARR; R J RANDALL
Journal:  J Biol Chem       Date:  1951-11       Impact factor: 5.157

4.  The nucleic acids of plant tissues; the extraction and estimation of desoxypentose nucleic acid and pentose nucleic acid.

Authors:  M OGUR; G ROSEN
Journal:  Arch Biochem       Date:  1950-02

5.  Liver Tumors in Rats Fed Thiourea or Thioacetamide.

Authors:  O G Fitzhugh; A A Nelson
Journal:  Science       Date:  1948-12-03       Impact factor: 47.728

6.  Toxicity of thioacetamide.

Authors:  Z Hruban; W Gradman; A Slesers; M Lubran
Journal:  Lab Invest       Date:  1966-11       Impact factor: 5.662

  6 in total
  2 in total

1.  Differential reactivation of fetal/neonatal genes in mouse liver tumors induced in cirrhotic and non-cirrhotic conditions.

Authors:  Xi Chen; Masahiro Yamamoto; Kiyonaga Fujii; Yasuharu Nagahama; Takako Ooshio; Bing Xin; Yoko Okada; Hiroyuki Furukawa; Yuji Nishikawa
Journal:  Cancer Sci       Date:  2015-06-25       Impact factor: 6.716

2.  A carcinogenic potency database of the standardized results of animal bioassays.

Authors:  L S Gold; C B Sawyer; R Magaw; G M Backman; M de Veciana; R Levinson; N K Hooper; W R Havender; L Bernstein; R Peto
Journal:  Environ Health Perspect       Date:  1984-12       Impact factor: 9.031

  2 in total

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