Literature DB >> 4319199

Transfer of bilirubin uridine diphosphate-glucuronyltransferase to enzyme-deficient rats.

H E Rugstad, S H Robinson, C Yannoni, A H Tashjian.   

Abstract

Cells from a clonal strain (MH(1)C(1)) of rat hepatoma were transplanted subcutaneously into two homozygous Gunn rats, which are jaundiced because the enzyme bilirubin uridine diphosphate-glucuronyltransferase is absent from the liver. Because of the enzyme activity present in the transplanted cells, the recipient rats developed the capacity to conjugate bilirubin and reverted in large part to a normal pattern of bilirubin excretion.

Entities:  

Mesh：

Substances：

Year:  1970        PMID： 4319199     DOI： 10.1126/science.170.3957.553

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  8 in total

Review 1.  Genetic modification of xenografts.

Authors:  J L Platt
Journal:  Curr Top Microbiol Immunol       Date:  2003       Impact factor: 4.291

Review 2.  Stem cell therapy. Use of differentiated pluripotent stem cells as replacement therapy for treating disease.

Authors:  Ira J Fox; George Q Daley; Steven A Goldman; Johnny Huard; Timothy J Kamp; Massimo Trucco
Journal:  Science       Date:  2014-08-22       Impact factor: 47.728

3.  Bilirubin glucuronidation by intact Gunn rat fibroblasts expressing bilirubin UDP-glucuronosyltransferase.

Authors:  J Seppen; K Tada; S Hellwig; C T Bakker; V R Prasad; N Roy Chowdhury; J Roy Chowdhury; P J Bosma; R P Oude Elferink
Journal:  Biochem J       Date:  1996-03-01       Impact factor: 3.857

4.  An experimental method for rapid growth of liver in spleen. The survival and proliferation of chemically induced preneoplastic hepatocytes in spleen.

Authors:  S D Finkelstein; G Lee; A Medline; M Tatematsu; L Makowka; E Farber
Journal:  Am J Pathol       Date:  1983-02       Impact factor: 4.307

5.  Estrogen induction of growth factors specific for hormone-responsive mammary, pituitary, and kidney tumor cells.

Authors:  D A Sirbasku
Journal:  Proc Natl Acad Sci U S A       Date:  1978-08       Impact factor: 11.205

6.  The history and use of human hepatocytes for the treatment of liver diseases: the first 100 patients.

Authors:  Marc C Hansel; Roberto Gramignoli; Kristen J Skvorak; Kenneth Dorko; Fabio Marongiu; William Blake; Julio Davila; Stephen C Strom
Journal:  Curr Protoc Toxicol       Date:  2014-11-06

Review 7.  Cellular Transplantation for Liver Diseases.

Authors:  Elizabeth Jameson
Journal:  Gastroenterology Res       Date:  2008-11-20

8.  Novel strategy for hepatocyte transplantation using resected organ with hepatocellular carcinoma or cholangiocarcinoma after hepatectomy.

Authors:  Toki Kawai; Masahiro Ito; Chihiro Hayashi; Naoki Yamamoto; Yukio Asano; Satoshi Arakawa; Akihiko Horiguchi
Journal:  Fujita Med J       Date:  2019-11-02
  8 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.