Literature DB >> 43173

The actions of 5-hydroxytryptamine and histamine on the isolated ileum of the tree shrew (Tupaia glis).

K Sakai, Y Shiraki, T Tatsumi, K Tsuji.   

Abstract

1. Contractions to 5-hydroxytryptamine (5-HT) and histamine of longitudinal muscle from the isolated ileum of the tree shrew (Tupaia), guinea-pig and rat were investigated by constructing dose-response curves and studying the effects of various antagonists. 2 In the Tupaia and rat ileum the contraction to 5-HT was reduced by methysergide but not affected by tetrodotoxin (TTX), morphine, hexamethonium (C6) or atropine. The response of guinea-pig ileum to 5-HT was not significantly inhibited by methysergide or C6, but was blocked by TTX, morphine and atropine. 3 Histamine-induced contraction of Tupaia and guinea-pig ileum was antagonized by diphenhydramine but not by TTX, morphine, C6 or atropine. Histamine was almost without effect on the rat ileum.

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Year:  1979        PMID： 43173      PMCID： PMC2043660          DOI： 10.1111/j.1476-5381.1979.tb10845.x

Source DB:  PubMed          Journal:  Br J Pharmacol        ISSN： 0007-1188            Impact factor:   8.739


  11 in total

1.  Drugs which antagonize 5-hydroxytryptamine.

Authors:  J H GADDUM; K A HAMEED
Journal:  Br J Pharmacol Chemother       Date:  1954-06

2.  An antagonism of 5-hydroxytryptamine by atropine.

Authors:  P A ROBERTSON
Journal:  J Physiol       Date:  1953-08       Impact factor: 5.182

3.  A preliminary investigation of the pharmacology of longitudinal muscle strips from human isolated jejunum.

Authors:  B Whitney
Journal:  J Pharm Pharmacol       Date:  1965-08       Impact factor: 3.765

4.  A pharmacological investigation of human isolated ileum.

Authors:  A Bennett
Journal:  Nature       Date:  1965-12-25       Impact factor: 49.962

5.  Breeding tupaias (Tupaia belangeri) in captivity.

Authors:  A Schwaier
Journal:  Z Versuchstierkd       Date:  1973

6.  A set theoretical approach to immunotaxonomy: analysis of species comparisons in modified Ochterlony plates.

Authors:  G W Moore; M Goodman
Journal:  Bull Math Biophys       Date:  1968-06

7.  A pharmacological analysis of the mode of action of serotonin (5-hydroxytryptamine) upon the guinea-pig ileum.

Authors:  M ROCHA E SILVA; J R VALLE; P PICARELLI
Journal:  Br J Pharmacol Chemother       Date:  1953-12

8.  Two kinds of tryptamine receptor.

Authors:  J H GADDUM; Z P PICARELLI
Journal:  Br J Pharmacol Chemother       Date:  1957-09

9.  An analysis of the direct and indirect actions of drugs on the isolated guinea-pig ileum.

Authors:  M DAY; J R VANE
Journal:  Br J Pharmacol Chemother       Date:  1963-02

10.  THE SITE OF THE 5-HYDROXYTRYPTAMINE RECEPTOR ON THE INTRAMURAL NERVOUS PLEXUS OF THE GUINEA-PIG ISOLATED ILEUM.

Authors:  G BROWNLEE; E S JOHNSON
Journal:  Br J Pharmacol Chemother       Date:  1963-10
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  7 in total

1.  Demonstration in Tupaia papillary muscle preparations of alpha-adrenoceptors mediating positive inotropic effects: comparison with guinea-pigs.

Authors:  T Koga; Y Shiraki; K Sakai
Journal:  Br J Pharmacol       Date:  1989-10       Impact factor: 8.739

2.  A pharmacological analysis of the contractile action of histamine upon the ileal region of the isolated, blood-perfused small intestine of the rat.

Authors:  K Sakai
Journal:  Br J Pharmacol       Date:  1979-12       Impact factor: 8.739

3.  Pharmacological investigation into the effects of histamine and histamine analogues on guinea-pig and rat colon in vitro.

Authors:  M J Aguilar; F J Morales-Olivas; E Rubio
Journal:  Br J Pharmacol       Date:  1986-07       Impact factor: 8.739

4.  Effects of serotonin on the internal anal sphincter: in vivo manometric study in rats.

Authors:  M Goldberg; M Hanani; S Nissan
Journal:  Gut       Date:  1986-01       Impact factor: 23.059

5.  The enteric neural receptor for 5-hydroxytryptamine.

Authors:  M D Gershon; M Takaki; H Tamir; T Branchek
Journal:  Experientia       Date:  1985-07-15

6.  Alpha 2-adrenoceptor antagonism and other pharmacological antagonist properties of some substituted benzoquinolizines and yohimbine in vitro.

Authors:  N Lattimer; R P McAdams; K F Rhodes; S Sharma; S J Turner; J F Waterfall
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1984-10       Impact factor: 3.000

7.  Pardaxin produces postjunctional muscle contraction in guinea-pig intestinal smooth muscle.

Authors:  N Primor
Journal:  Br J Pharmacol       Date:  1984-05       Impact factor: 8.739
  7 in total

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