Literature DB >> 4312756

Radical transformation in irradiated DNA and its constituents.

J N Herak, V Galogaza.   

Abstract

Electron spin resonance spectroscopy has been used to study transformation of radicals in DNA and a number of its constituents. It was found that in all the bases irradiated at 77 degrees K, hydrogen-addition radicals were formed on warming. The following mechanism of radical transformation has been proposed: damaged species, probably ion-radicals, release hydrogen atoms on warming, which then add to the undamaged bases, preferentially thymine. Thymine need not be the place of the primary damage.

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Year:  1969        PMID： 4312756      PMCID： PMC286118          DOI： 10.1073/pnas.64.1.8

Source DB:  PubMed          Journal:  Proc Natl Acad Sci U S A        ISSN： 0027-8424            Impact factor:   11.205


  9 in total

1.  ELECTRON SPIN RESONANCE OF IRRADIATED DNA.

Authors:  P S PERSHAN; R G SHULMAN; B J WYLUDA; J EISINGER
Journal:  Science       Date:  1965-04-16       Impact factor: 47.728

2.  SOME RADIATION EFFECTS ON DNA AND ITS CONSTITUENTS.

Authors:  W GORDY; B PRUDEN; W SNIPES
Journal:  Proc Natl Acad Sci U S A       Date:  1965-04       Impact factor: 11.205

3.  Electron spin resonance of an irradiated single crystal of Guanine hydrochloride dihydrate.

Authors:  C Alexander; W Gordy
Journal:  Proc Natl Acad Sci U S A       Date:  1967-10       Impact factor: 11.205

4.  FREE RADICALS FORMED BY HYDROGEN ATOM BOMBARDMENT OF THE NUCLEIC-ACID BASES.

Authors:  J N Herak; W Gordy
Journal:  Proc Natl Acad Sci U S A       Date:  1965-11       Impact factor: 11.205

5.  Electron spin resonance of an irradiated single crystal of deoxyadenosine monohydrate.

Authors:  J J Lichter; W Gordy
Journal:  Proc Natl Acad Sci U S A       Date:  1968-06       Impact factor: 11.205

6.  ESR study of nucleosides and nucleotides bombarded with hydrogen atoms.

Authors:  J N Herak; W Gordy
Journal:  Proc Natl Acad Sci U S A       Date:  1966-07       Impact factor: 11.205

7.  Electron spin resonance of an irradiated single crystal of thymidine.

Authors:  B Pruden; W Snipes; W Gordy
Journal:  Proc Natl Acad Sci U S A       Date:  1965-05       Impact factor: 11.205

8.  ESR study of gamma-irradiated polynucleotides.

Authors:  J N Herak; W Gordy
Journal:  Proc Natl Acad Sci U S A       Date:  1966-04       Impact factor: 11.205

Review 9.  Polarographic behavior of nucleosides and nucleotides of purines, pyrimidines, pyridines, and flavins.

Authors:  B Janík; P J Elving
Journal:  Chem Rev       Date:  1968-06       Impact factor: 60.622
  9 in total

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