Literature DB >> 4305968

Diphtheria toxin subunit active in vitro.

R J Collier, H A Cole.   

Abstract

Exposure of diphtheria toxin to dithiothreitol (and similar thiols) resulted in a subunit which was active in catalyzing the adenosine diphosphateribosylation of mammalian aminoacyl-transferase II in the presence of nicotinamide adenine dinucleotide. At the same time there was a marked increase in total ADP-ribosylation activity. A molecule which was apparently identical to the derived subunit in size and activity was detected in partially purified preparations of toxin.

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Year:  1969        PMID： 4305968     DOI： 10.1126/science.164.3884.1179

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  26 in total

Review 1.  Diphtheria toxin: mode of action and structure.

Authors:  R J Collier
Journal:  Bacteriol Rev       Date:  1975-03

2.  Combining affinity purification by ADP-ribose-binding macro domains with mass spectrometry to define the mammalian ADP-ribosyl proteome.

Authors:  Nadia Dani; Annalisa Stilla; Adriano Marchegiani; Antonio Tamburro; Susanne Till; Andreas G Ladurner; Daniela Corda; Maria Di Girolamo
Journal:  Proc Natl Acad Sci U S A       Date:  2009-02-25       Impact factor: 11.205

3.  Endogenous ADP-ribosylation of elongation factor 2 in polyoma virus-transformed baby hamster kidney cells.

Authors:  J L Fendrick; W J Iglewski
Journal:  Proc Natl Acad Sci U S A       Date:  1989-01       Impact factor: 11.205

4.  Pasteurella multocida toxin as a transporter of non-cell-permeating proteins.

Authors:  Stefan Bergmann; Doris Jehle; Carsten Schwan; Joachim H C Orth; Klaus Aktories
Journal:  Infect Immun       Date:  2013-04-29       Impact factor: 3.441

5.  Response of cultured mammalian cells to diphtheria toxin. V. Concurrent resistance to ribonucleic acid viruses in diphtheria toxin-resistant KB cell strains.

Authors:  T J Moehring; J M Moehring
Journal:  Infect Immun       Date:  1972-10       Impact factor: 3.441

Review 6.  Corynebacterium diphtheriae and its relatives.

Authors:  L Barksdale
Journal:  Bacteriol Rev       Date:  1970-12

7.  Toxic proteins inhibiting protein synthesis.

Authors:  S Olsnes
Journal:  Naturwissenschaften       Date:  1972-11

8.  Botulinal toxins and the problem of nomenclature of simple toxins.

Authors:  C Lamanna; G Sakaguchi
Journal:  Bacteriol Rev       Date:  1971-09

9.  Neurotransmitter release is blocked intracellularly by botulinum neurotoxin, and this requires uptake of both toxin polypeptides by a process mediated by the larger chain.

Authors:  B Poulain; L Tauc; E A Maisey; J D Wadsworth; P M Mohan; J O Dolly
Journal:  Proc Natl Acad Sci U S A       Date:  1988-06       Impact factor: 11.205

10.  Studies on the mode of action of diphtheria toxin. V. Protein metabolism in a guinea pig model simulating chronic diphtheritic toxemia.

Authors:  P F Bonventre
Journal:  Infect Immun       Date:  1973-04       Impact factor: 3.441
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