Literature DB >> 4305967

Adenyl cyclase activity in rat pineal gland: effects of chronic denervation and norepinephrine.

B Weiss, E Costa.   

Abstract

Adenyl cyclase activity in the pineal gland of rats was determined by measuring the rate of formation of radioactive cyclic 3',5'-adenosine monophosphate from (14)C-labeled adenosine triphosphate. Norepinephrine added in vitro to pineal homogenates enhanced this activity, while denervation of the pineal gland by superior cervical ganglionectomy did not significantly reduce it. The enzyme in these denervated glands was more responsive to the stimulatory effects of norepinephrine.

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Year:  1967        PMID： 4305967     DOI： 10.1126/science.156.3783.1750

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  15 in total

1.  Heat-stable low molecular weight form of phosphodiesterases from bovine pineal gland.

Authors:  K Sankaran; I Hanbauer; W Lovenberg
Journal:  Proc Natl Acad Sci U S A       Date:  1978-07       Impact factor: 11.205

2.  Regulation of sensitivity to beta-adrenergic stimulation in induction of pineal N-acetyltransferase.

Authors:  J A Romero; J Axelrod
Journal:  Proc Natl Acad Sci U S A       Date:  1975-05       Impact factor: 11.205

3.  Regulation of dopamine receptor sensitivity by an endogenous protein activator or adenylate cyclase.

Authors:  E Costa; M G Gnegy; P Uzunov
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1977       Impact factor: 3.000

4.  Single-dose tolerance to the behavioral effects of dibutyryl cyclic AMP in mice.

Authors:  M Weiner; J W Olson
Journal:  Psychopharmacology (Berl)       Date:  1977-08-31       Impact factor: 4.530

5.  The stimulating action of gastrin pentapeptide and histamine on adenyl cyclase activity in rat stomach.

Authors:  R I Bersimbaev; S V Argutinskaya; R I Salganik
Journal:  Experientia       Date:  1971-12-15

6.  Input and output signals in a model neural system: the regulation of melatonin production in the pineal gland.

Authors:  D C Klein; J Weller
Journal:  In Vitro       Date:  1970 Nov-Dec

7.  Ultracytochemical localisation and comparison of adenyl cyclase activities in pineal bodies of Wistar rats and Mongolian gerbils.

Authors:  R Krstić
Journal:  Histochemistry       Date:  1977-08-22

8.  Stimulation by dopamine of adenylate cyclase in retinal homogenates and of adenosine-3':5'-cyclic monophosphate formation in intact retina.

Authors:  J H Brown; M H Makman
Journal:  Proc Natl Acad Sci U S A       Date:  1972-03       Impact factor: 11.205

9.  Control of pineal indole biosynthesis by changes in sympathetic tone caused by factors other than environmental lighting.

Authors:  H J Lynch; J P Eng; R J Wurtman
Journal:  Proc Natl Acad Sci U S A       Date:  1973-06       Impact factor: 11.205

10.  Effect of pinealectomy on arterial blood pressure and food and water intake in the rat.

Authors:  A Zanoboni; A Forni; W Zanoboni-Muciaccia; C Zanussi
Journal:  J Endocrinol Invest       Date:  1978-04       Impact factor: 4.256
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