Literature DB >> 4304859

Molecular order of participation of inhibitors (or activators) in biological systems.

R B Loftfield, E A Eigner.   

Abstract

From a Hill plot it is frequently possible to determine whether exactly one, two, or several inhibitor (or activator) molecules are involved in a critical rate-determining biological process.

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Substances：

Year:  1969        PMID： 4304859     DOI： 10.1126/science.164.3877.305

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  14 in total

1.  alpha-1-Anti-trypsin, an inhibitor of renin.

Authors:  S Scharpé; M Eid; W Cooreman; A Lauwers
Journal:  Biochem J       Date:  1976-02-01       Impact factor: 3.857

2.  Channel-opening kinetic mechanism for human wild-type GluK2 and the M867I mutant kainate receptor.

Authors:  Yan Han; Congzhou Wang; Jae Seon Park; Li Niu
Journal:  Biochemistry       Date:  2010-11-02       Impact factor: 3.162

3.  Rabbit distal colon epithelium: II. Characterization of (Na+,K+,Cl-)-cotransport and [3H]-bumetanide binding.

Authors:  H Wiener; C H van Os
Journal:  J Membr Biol       Date:  1989-09       Impact factor: 1.843

4.  Microbial L-phenylalanine ammonia-lyase. Purification, subunit structure and kinetic properties of the enzyme from Rhizoctonia solani.

Authors:  K K Kalghatgi; P V Subba Rao
Journal:  Biochem J       Date:  1975-07       Impact factor: 3.857

5.  Modification of the erythrocyte membrane by sulfhydryl group reagents.

Authors:  D V Godin; S L Schrier
Journal:  J Membr Biol       Date:  1972-12       Impact factor: 1.843

6.  COMPT, a time-sharing program for nonlinear regression analysis of compartmental models of drug distribution.

Authors:  M Pfeffer
Journal:  J Pharmacokinet Biopharm       Date:  1973-04

7.  Structure-activity relationship of reversible cholinesterase inhibitors including paraquat.

Authors:  Y Seto; T Shinohara
Journal:  Arch Toxicol       Date:  1988-08       Impact factor: 5.153

8.  In vitro effects of pure polychlorinated biphenyl isomers on the rabbit muscle lactate dehydrogenase.

Authors:  M Nishizawa; T Ohyama
Journal:  Bull Environ Contam Toxicol       Date:  1980-10       Impact factor: 2.151

9.  Conformational changes during enzyme catalysis: role of water in the transition state.

Authors:  R B Loftfield; E A Eigner; A Pastuszyn; T N Lövgren; H Jakubowski
Journal:  Proc Natl Acad Sci U S A       Date:  1980-06       Impact factor: 11.205

10.  Peptidyl-puromycin synthesis on polyribosomes from Escherichia coli.

Authors:  S Pestka
Journal:  Proc Natl Acad Sci U S A       Date:  1972-03       Impact factor: 11.205
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