Literature DB >> 430478

Antianaphylactic agents. 1. 2-(Acylamino)oxazoles.

W J Ross, R G Harrison, M R Jolley, M C Neville, A Todd, J P Verge, W Dawson, W J Sweatman.   

Abstract

The synthesis and biological properties of 35 2-(acylamino)oxazoles are described. The majority of the compounds inhibit the release of slow-reacting substance of anaphylaxis (SRS-A) in vitro from sensitized guinea pig chopped lung. In addition, several of the compounds inhibited the release of SRS-A from passively sensitized human chopped lung and protected guinea pigs from the effects of anaphylaxis in a modified Herxheimer test.

Entities:  

Mesh：

Substances：

Year:  1979        PMID： 430478     DOI： 10.1021/jm00190a011

Source DB:  PubMed          Journal:  J Med Chem        ISSN： 0022-2623            Impact factor:   7.446


  5 in total

1.  Nickel-Catalyzed [2+2+2] Cycloaddition of Diynes and Cyanamides.

Authors:  Ryan M Stolley; Michael T Maczka; Janis Louie
Journal:  European J Org Chem       Date:  2011-07

2.  A simple method for the electrophilic cyanation of secondary amines.

Authors:  Chen Zhu; Ji-Bao Xia; Chuo Chen
Journal:  Org Lett       Date:  2013-12-06       Impact factor: 6.005

3.  Dissociation between the anti-anaphylactic and the anti-histaminic actions of ketotifen.

Authors:  U Martin; M Baggiolini
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1981-04       Impact factor: 3.000

4.  The effect of prednisolone and ketotifen on the antigen-induced bronchoconstriction and mediator release in rat isolated lungs.

Authors:  M Ottenhof; J G Ufkes; H H Van Rooij
Journal:  Br J Pharmacol       Date:  1985-11       Impact factor: 8.739

5.  The pharmacology of isamoxole [2-methyl-n-butyl-n(4-methyloxazol-2-yl) propanamide] LRCL 3950, a new anti-allergic compound.

Authors:  W Dawson; W J Sweatman
Journal:  Br J Pharmacol       Date:  1980       Impact factor: 8.739
  5 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.