Literature DB >> 4303081

Prostaglandin stimulation of rat corticosteroidogenesis.

J D Flack, R Jessup, P W Ramwell.   

Abstract

Prostaglandins and their C20:(omega)6 fatty acid precursors are present in rat adrenal glands. Small doses of prostaglandins (PGE(1), PGE(2), or PGF(1infinity) 1.4 to 2.4 micromolar) increased steroidogenesis in the superfused adrenal glands obtained from hypophysectomized rats. This effect was mimicked in part by both adrenocorticotropin and its postulated intracellular intermediate adenosine 3', 5'-cyclic monophosphate; all three responses were inhibited by cycloheximide.

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Year:  1969        PMID: 4303081     DOI: 10.1126/science.163.3868.691

Source DB:  PubMed          Journal:  Science        ISSN: 0036-8075            Impact factor:   47.728


  15 in total

1.  Nicotine-induced stimulation of steroidogenesis in adrenocortical cells of the cat.

Authors:  R P Rubin; W Warner
Journal:  Br J Pharmacol       Date:  1975-03       Impact factor: 8.739

2.  Immune cells and cytokine circuits: toward a working model for understanding direct immune-to-adrenal communication pathways.

Authors:  Terrence Deak
Journal:  Endocrinology       Date:  2008-04       Impact factor: 4.736

3.  Intracellular production of adrenal renin in the fetal mouse. An immuno-electron microscopical study.

Authors:  Y Kon; Y Hashimoto; H Kitagawa; M Sugimura; K Murakami
Journal:  J Anat       Date:  1991-06       Impact factor: 2.610

4.  Temporal effects of ACTH, indomethacin and 7-oxa-13-prostynoic acid upon glucocorticoid production by the human adrenal.

Authors:  K V Honn; W Chavin
Journal:  Experientia       Date:  1977-04-15

5.  Adrenocortical steroidogenesis: the effects of prostaglandins.

Authors:  T Saruta; N M Kaplan
Journal:  J Clin Invest       Date:  1972-09       Impact factor: 14.808

Review 6.  Biological significance of prostaglandins with special reference to their effects on metabolism.

Authors:  J R Weeks
Journal:  Naunyn Schmiedebergs Arch Pharmakol       Date:  1971

7.  Fatty acid composition of the sterol ester fraction of human adrenal cortex in Cushingś syndrome and after treatment with aminoglutethimide.

Authors:  P R Raggatt; L L Engel; T Symington
Journal:  Lipids       Date:  1972-07       Impact factor: 1.880

8.  Caesarean section and respiratory distress syndrome.

Authors:  I F Csaba; E Sulyok; J Hadnagy
Journal:  Br Med J       Date:  1977-04-09

9.  Effect of prostaglandin E 1 on certain renal actions of parathyroid hormone.

Authors:  N P Beck; F R DeRubertis; M F Michelis; R D Fusco; J B Field; B B Davis
Journal:  J Clin Invest       Date:  1972-09       Impact factor: 14.808

10.  Release of pituitary growth hormone by prostaglandins and dibutyryl adenosine cyclic 3':5'-monophosphate in the absence of protein synthesis.

Authors:  R M MacLeod; J E Lehmeyer
Journal:  Proc Natl Acad Sci U S A       Date:  1970-11       Impact factor: 11.205

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