Literature DB >> 4300767

Acute necrotizing lepromatous lymphadenitis: an erythema-nodosum-leprosum-like reaction in lymph nodes.

A B Karat, S Karat, C K Job, D Sudarsanam.   

Abstract

Histological examination of lymph-node biopsy specimens in 12 patients with erythema nodosum leprosum showed almost complete replacement of the node by lepromatous granuloma, together with considerable polymorph infiltration. Ziehl-Neelsen staining demonstrated numerous Mycobacterium leprae present in the nodes. The majority of these patients were very ill, and responded to prednisolone or corticotrophin.It is suggested that the histological appearances may represent an intensive inflammatory response in the lymph nodes followed by avascular aseptic necrosis.

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Year:  1968        PMID: 4300767      PMCID: PMC1912167          DOI: 10.1136/bmj.4.5625.223

Source DB:  PubMed          Journal:  Br Med J        ISSN: 0007-1447


  5 in total

1.  A bacteriologic study of erythema nodosum leprosum.

Authors:  D S RIDLEY
Journal:  Int J Lepr       Date:  1960 Jul-Sep

2.  Reactional states in leprosy.

Authors:  N S CAMPOS; P R DE SOUZA
Journal:  Int J Lepr       Date:  1954 Jul-Sep

3.  Streptomycin and INAH in the treatment of leprosy. A preliminary communication.

Authors:  A B Karat; P S Rao; S Karat; C K Job
Journal:  Lepr Rev       Date:  1967-07       Impact factor: 0.537

4.  Nerve abscess in lepromatous leprosy--report of a patient.

Authors:  C K Job; C Bhaktaviziam
Journal:  Lepr Rev       Date:  1967-10       Impact factor: 0.537

5.  Acute exudative arthritis in leprosy--rheumatoid-arthritis-like syndrome in association with erythema nodosum leprosum.

Authors:  A B Karat; S Karat; C K Job; M A Furness
Journal:  Br Med J       Date:  1967-09-23
  5 in total
  4 in total

1.  Use of thalidomide in leprosy.

Authors:  M F Waters
Journal:  BMJ       Date:  1991-08-24

2.  Immune responses in mice with murine leprosy.

Authors:  W Ptak; J M Gaugas; R J Rees; A C Allison
Journal:  Clin Exp Immunol       Date:  1970-01       Impact factor: 4.330

3.  Mycobacterium tuberculosis infection is associated with the development of erythema nodosum and nodular vasculitis.

Authors:  Sheng'an Chen; Jiazhen Chen; Lianjun Chen; Qiao'an Zhang; Xiaoqun Luo; Wenhong Zhang
Journal:  PLoS One       Date:  2013-05-01       Impact factor: 3.240

4.  Histopathological study of ocular erythema nodosum leprosum and post-therapeutic scleral perforation: a case report.

Authors:  S R Rathinam; Hadi M Khazaei; C K Job
Journal:  Indian J Ophthalmol       Date:  2008 Sep-Oct       Impact factor: 1.848

  4 in total

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