| Literature DB >> 4300045 |
Abstract
Significant alcohol dehydrogenase activity has been demonstrated in the soluble fraction of rat brain and is very similar to the liver enzyme in kinetic properties and responses to inhibitors. A cerebral mechanism that oxidizes ethanol may play a significant role in local adjustments during exposure to ethanol and in the pathogenesis of the neural disorders associated with chronic alcohol ingestion or withdrawal.Entities:
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Year: 1968 PMID： 4300045 DOI： 10.1126/science.162.3849.131
Source DB: PubMed Journal: Science ISSN： 0036-8075 Impact factor: 47.728