Literature DB >> 4298142

Cyclic 3',5'-adenosine monophosphate phosphodiesterase produced by the slime mold Dictyostelium discoideum.

Y Y Chang.   

Abstract

An enzyme that hydrolyzes cyclic ',5'-adenosine monophosphate to 5'-adenosine monophosphate was found in the culture medium of the cellular slime mold Dictyostelium discoidum. The enzymatic activity shows a pH optimum of 7.5, and magnesium is required for maximum activity. The enzyme is not inhibited by caffeine. It has a Michaelis-Menten constant of 2 x 10(-3)M and its molecular weight is around 300,000.

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Year:  1968        PMID： 4298142     DOI： 10.1126/science.161.3836.57

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  30 in total

1.  Comparative effects of adenosine and adenine and guanine nucleotides on drug biotransformation in rats.

Authors:  M Weiner
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1975       Impact factor: 3.000

2.  A genetic study of aggregation in the cellular slime mould Dictyostelium discoideum using complementation analysis.

Authors:  K L Williams; P C Newell
Journal:  Genetics       Date:  1976-02       Impact factor: 4.562

3.  Interaction of cAMP with the cell-surface receptor induces cell-type-specific mRNA accumulation in Dictyostelium discoideum.

Authors:  M Oyama; D D Blumberg
Journal:  Proc Natl Acad Sci U S A       Date:  1986-07       Impact factor: 11.205

4.  Preliminary characterization of the acrasin of the cellular slime mold Polysphondylium violaceum.

Authors:  B Wurster; P Pan; G G Tyan; J T Bonner
Journal:  Proc Natl Acad Sci U S A       Date:  1976-03       Impact factor: 11.205

5.  Stimulation of cell aggregation by theophylline in the asexual reproduction of fresh-water sponges (Ephydatia fluviatilis).

Authors:  R Rasmont
Journal:  Experientia       Date:  1974-07-15

6.  3':5'-cyclic adenosine monophosphate phosphodiesterase: negative cooperativity.

Authors:  T R Russell; W J Thompson; F W Schneider; M M Appleman
Journal:  Proc Natl Acad Sci U S A       Date:  1972-07       Impact factor: 11.205

7.  Inhibition of aggregation and differentiation of Dictyostelium discoideum by antibodies against adenosine 3':5'-cyclic monophosphate diesterase.

Authors:  E A Goidl; B M Chassy; L L Love; M I Krichevsky
Journal:  Proc Natl Acad Sci U S A       Date:  1972-05       Impact factor: 11.205

8.  A cAMP signaling model explains the benefit of maintaining two forms of phosphodiesterase in Dictyostelium.

Authors:  Eiríkur Pálsson
Journal:  Biophys J       Date:  2009-11-04       Impact factor: 4.033

9.  Unified mechanism for relay and oscillation of cyclic AMP in Dictyostelium discoideum.

Authors:  A Goldbeter; L A Segel
Journal:  Proc Natl Acad Sci U S A       Date:  1977-04       Impact factor: 11.205

10.  Folic acid deaminase activity during development in Dictyostelium discoideum.

Authors:  P I Kakebeeke; R J de Wit; T M Konijn
Journal:  J Bacteriol       Date:  1980-07       Impact factor: 3.490
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