Literature DB >> 42967

Stimulation of heart rate by insulin: uninfluenced by beta-adrenergic receptor blockade in rabbits.

F Jacobsen, N J Christensen.   

Abstract

Intravenous injection of insulin increased heart rate approximately 20% in six alloxan-diabetic rabbits. Blood glucose concentrations after insulin did not decrease below the fasting level of non-diabetic animals and none of the rabbits had signs of hypoglycermia. Intravenous injection of saline or insulin solvent had no effect on heart rate. The stimulatory effect of insulin on heart rate was not influenced by autonomic nervous blockade by propranolol or by propranolol plus atropine.

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Year:  1979        PMID： 42967     DOI： 10.1080/00365517909106102

Source DB:  PubMed          Journal:  Scand J Clin Lab Invest        ISSN： 0036-5513            Impact factor:   1.713


  10 in total

Review 1.  Catecholamines and diabetes mellitus.

Authors:  N J Christensen
Journal:  Diabetologia       Date:  1979-04       Impact factor: 10.122

Review 2.  Acute effects of insulin on cardiovascular function and noradrenaline uptake and release.

Authors:  N J Christensen
Journal:  Diabetologia       Date:  1983-11       Impact factor: 10.122

3.  Intravenous insulin decreases urinary albumin excretion in long-term diabetics with nephropathy.

Authors:  N J Christensen; H J Gundersen; C E Mogensen; E Vittinghus
Journal:  Diabetologia       Date:  1980-04       Impact factor: 10.122

4.  The effects of insulin-induced hypoglycaemia on cardiovascular function in normal man: studies using radionuclide ventriculography.

Authors:  B M Fisher; G Gillen; H J Dargie; G C Inglis; B M Frier
Journal:  Diabetologia       Date:  1987-11       Impact factor: 10.122

5.  Studies on the insulin-antagonistic effect of catecholamines in normal man. Evidence for the importance of beta 2-receptors.

Authors:  I Lager; S Attvall; B M Eriksson; H von Schenk; U Smith
Journal:  Diabetologia       Date:  1986-07       Impact factor: 10.122

6.  Insulin-induced increase in heart rate and its prevention by propranolol.

Authors:  A Siani; P Strazzullo; N Giorgione; A De Leo; M Mancini
Journal:  Eur J Clin Pharmacol       Date:  1990       Impact factor: 2.953

7.  Abnormal regulation of sympathetic nervous activity and heart rate after oral glucose in type 1 (insulin-dependent) diabetic patients.

Authors:  L Hegedüs; N J Christensen; L Sestoft
Journal:  Diabetologia       Date:  1983-09       Impact factor: 10.122

8.  The influence of glucose-induced hyperinsulinaemia on renal glomerular function and circulating catecholamines in normal man.

Authors:  G C Viberti; C R Strakosch; H Keen; D Mackintosh; N Dalton; P D Home
Journal:  Diabetologia       Date:  1981-11       Impact factor: 10.122

9.  The acute effect of insulin on heart rate, blood pressure, plasma noradrenaline and urinary albumin excretion. The role of changes in blood glucose.

Authors:  C E Mogensen; N J Christensen; H J Gundersen
Journal:  Diabetologia       Date:  1980-06       Impact factor: 10.122

10.  Effect of the long-acting insulin analogues glargine and degludec on cardiomyocyte cell signalling and function.

Authors:  Thorsten Hartmann; Sabrina Overhagen; D Margriet Ouwens; Silja Raschke; Paulus Wohlfart; Norbert Tennagels; Nina Wronkowitz; Jürgen Eckel
Journal:  Cardiovasc Diabetol       Date:  2016-07-15       Impact factor: 9.951
  10 in total

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