| Literature DB >> 4294481 |
P A Miller, K P Milstrey, P W Trown.
Abstract
Gliotoxin inhibits intracellular replication of poliovirus in HeLa cells at a stage subsequent to adsorption and penetration of virus. The sensitive step is synthesis of viral RNA: synthesis of viral protein is unaffected except as a consequence of blockade of RNA synthesis. Concentrations of gliotoxin sufficient to block viral RNA synthesis completely do not affect cellular RNA synthesis.Entities:
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Year: 1968 PMID： 4294481 DOI： 10.1126/science.159.3813.431
Source DB: PubMed Journal: Science ISSN： 0036-8075 Impact factor: 47.728