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Literature DB >> 4293082

Role of S-adenosylmethionine in methionine biosynthesis in yeast.

Abstract

Extracts of Saccharomyces cerevisiae were used to develop a cell-free system capable of converting the beta-carbon of serine into the methyl group of methionine. No requirement for either S-adenosylmethionine or S-adenosylhomocysteine could be demonstrated for net methionine biosynthesis. Growth of the cells in B(12) did not affect the reaction. The mechanism for the methylation of homocysteine in yeast appears to be similar to the non-B(12) system in Escherichia coli.

Entities: Chemical Species

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Year: 1967 PMID： 4293082 PMCID： PMC276763 DOI： 10.1128/jb.94.4.966-971.1967

Source DB: PubMed Journal: J Bacteriol ISSN： 0021-9193 Impact factor: 3.490

23 in total

1. BIOSYNTHESIS OF METHIONINE IN SACCHAROMYCES CEREVISIAE. PARTIAL PURIFICATION AND PROPERTIES OF S-ADENOSYLMETHIONINE: HOMOCYSTEINE METHYLTRANSFERASE.

Authors: S K SHAPIRO; D A YPHANTIS; A ALMENAS
Journal: J Biol Chem Date: 1964-05 Impact factor: 5.157

2. STUDIES ON THE TERMINAL REACTION IN THE BIOSYNTHESIS OF METHIONINE.

Authors: H WEISSBACH; A PETERKOFSKY; B G REDFIELD; H DICKERMAN
Journal: J Biol Chem Date: 1963-10 Impact factor: 5.157

3. INTERRELATIONS BETWEEN TWO PATHWAYS OF METHIONINE BIOSYNTHESIS IN AEROBACTER AEROGENES.

Authors: J F MORNINGSTAR; R L KISLIUK
Journal: J Gen Microbiol Date: 1965-04

4. Preparation and properties of S-adenosyl-L-homocysteine, S-adenosyl-L-homocysteine sulfoxide and S-ribosyl-L-homocysteine.

Authors: J A DUERRE
Journal: Arch Biochem Biophys Date: 1962-01 Impact factor: 4.013

Review 1. The biosynthesis of methionine.

Authors: H Rüdiger; L Jaenicke
Journal: Mol Cell Biochem Date: 1973-06-27 Impact factor: 3.396

2. Methylation of homocysteine in Coprinus lagopus.

Authors: A R Salem; M A Foster; R H Wilson
Journal: Biochem J Date: 1970-06 Impact factor: 3.857

3. Serine transhydroxymethylase in methionine biosynthesis in Saccharomyces cerevisiae.

Authors: J L Botsford; L W Parks
Journal: J Bacteriol Date: 1969-03 Impact factor: 3.490

4. Sai-1 mutation: saccharomyces cerevisiae: characteristics of inhibition by S-adenosylmethonine and S-adenosylhomocysteine and protection by methionine.

Authors: K D Spence; S K Shapiro; N K Hutson
Journal: J Bacteriol Date: 1972-06 Impact factor: 3.490

5. Effects of glycine and serine on serine hydroxymethyltransferase levels in logarithmic cultures of Neurospora crassa Wild type and Ser-1-mutant.

Authors: E A Cossins; G Combepine; G Turian
Journal: Experientia Date: 1973-10-15

6. Influence of methionine pool composition on the formation of methyl-deficient transfer ribonucleic acid in Saccharomyces cerevisiae.

Authors: K Kjellin-Stråby
Journal: J Bacteriol Date: 1969-11 Impact factor: 3.490

6 in total

Role of S-adenosylmethionine in methionine biosynthesis in yeast.

1. BIOSYNTHESIS OF METHIONINE IN SACCHAROMYCES CEREVISIAE. PARTIAL PURIFICATION AND PROPERTIES OF S-ADENOSYLMETHIONINE: HOMOCYSTEINE METHYLTRANSFERASE.

2. STUDIES ON THE TERMINAL REACTION IN THE BIOSYNTHESIS OF METHIONINE.

3. INTERRELATIONS BETWEEN TWO PATHWAYS OF METHIONINE BIOSYNTHESIS IN AEROBACTER AEROGENES.

4. Preparation and properties of S-adenosyl-L-homocysteine, S-adenosyl-L-homocysteine sulfoxide and S-ribosyl-L-homocysteine.

5. Formation and metabolism of S-adenosyl-L-homocysteine in yeast.

6. Localization of S-adenosylmethionine in Candida utilis by ultraviolet microscopy.

7. Interrelationships between folic acid and cobalamin in the synthesis of methionine by extracts of Escherichia coli.

8. Two enzymic mechanisms for the methylation of homocysteine by extracts of Escherichia coli.

9. Preparation and properties of trimethylsulfonium-tetrahydrofolate methyltransferase.