Literature DB >> 4292835

A continuous recording technique for the measurement of carbon dioxide, and its application to mitochondrial oxidation and decarboxylation reactions.

D G Nicholls, D Shepherd, P B Garland.   

Abstract

1. A technique is described for continuously recording the concentration of carbon dioxide in mitochondrial suspensions. 2. The oxidation of palmitoylcarnitine by rat-liver mitochondria inhibits the oxidation of pyruvate and isocitrate, and stimulates the carboxylation of pyruvate. 3. These effects of palmitoylcarnitine oxidation are reversed by the uncoupling agent pentachlorophenol. 4. The effects of palmitoylcarnitine oxidation and pyruvate oxidation on the acylation of mitochondrial coenzyme A and reduction of nicotinamide nucleotides were measured. 5. Control mechanisms are discussed for the interactions between palmitoylcarnitine oxidation and the tricarboxylic acid cycle in rat-liver mitochondria.

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Year:  1967        PMID: 4292835      PMCID: PMC1270468          DOI: 10.1042/bj1030677

Source DB:  PubMed          Journal:  Biochem J        ISSN: 0264-6021            Impact factor:   3.857


  31 in total

1.  NICOTINAMIDE ADENINE DINUCLEOTIDE-SPECIFIC ISOCITRIC DEHYDROGENASE. A POSSIBLE REGULATORY PROTEIN.

Authors:  B D SANWAL; M W ZINK; C S STACHOW
Journal:  J Biol Chem       Date:  1964-05       Impact factor: 5.157

2.  THE EFFECT OF ADENYLIC ACID ON YEAST NICOTINAMIDE ADENINE DINUCLEOTIDE ISOCITRATE DEHYDROGENASE, A POSSIBLE METABOLIC CONTROL MECHANISM.

Authors:  J A HATHAWAY; D E ATKINSON
Journal:  J Biol Chem       Date:  1963-08       Impact factor: 5.157

3.  [ON THE MECHANISM OF GLUCONEOGENESIS AND ITS REGULATION. I. QUANTITATIVE DETERMINATION OF PYRUVATE CARBOXYLASE IN RAW EXTRACTS OF RAT LIVER].

Authors:  H V HENNING; W SEUBERT
Journal:  Biochem Z       Date:  1964-07-29

4.  The oxidation of glutamate by rat-heart sarcosomes.

Authors:  P BORST; E C SLATER
Journal:  Biochim Biophys Acta       Date:  1960-06-17

5.  Rapid measurement of the tension of carbon dioxide in blood.

Authors:  R W STOW; R F BAER; B F RANDALL
Journal:  Arch Phys Med Rehabil       Date:  1957-10       Impact factor: 3.966

6.  The respiratory chain and oxidative phosphorylation.

Authors:  B CHANCE; G R WILLIAMS
Journal:  Adv Enzymol Relat Subj Biochem       Date:  1956

7.  Biochemistry of fluoroacetate poisoning: the effect of fluorocitrate on purified aconitase.

Authors:  J F MORRISON; R A PETERS
Journal:  Biochem J       Date:  1954-11       Impact factor: 3.857

8.  Enzymatic synthesis of citric acid. II. Crystalline condensing enzyme.

Authors:  S OCHOA; J R STERN; M C SCHNEIDER
Journal:  J Biol Chem       Date:  1951-12       Impact factor: 5.157

9.  Paths of carbon in gluconeogenesis and lipogenesis: the role of mitochondria in supplying precursors of phosphoenolpyruvate.

Authors:  H A Lardy; V Paetkau; P Walter
Journal:  Proc Natl Acad Sci U S A       Date:  1965-06       Impact factor: 11.205

10.  Carnitine in intermediary metabolism. The metabolism of fatty acid esters of carnitine by mitochondria.

Authors:  J BREMER
Journal:  J Biol Chem       Date:  1962-12       Impact factor: 5.157

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  11 in total

1.  Alpha-keto acid dehydrogenase complexes. X. Regulation of the activity of the pyruvate dehydrogenase complex from beef kidney mitochondria by phosphorylation and dephosphorylation.

Authors:  T C Linn; F H Pettit; L J Reed
Journal:  Proc Natl Acad Sci U S A       Date:  1969-01       Impact factor: 11.205

2.  Aspects of ketogenesis: control and mechanism of ketone-body formation in isolated rat-liver mitochondria.

Authors:  M Lopes-Cardozo; I Mulder; F van Vugt; P G Hermans; S G van den Bergh; W Klazinga; E de Vries-Akkerman
Journal:  Mol Cell Biochem       Date:  1975-12-31       Impact factor: 3.396

3.  The regulation of triglyceride synthesis and fatty acid synthesis in rat epididymal adipose tissue. Effects of altered dietary and hormonal conditions.

Authors:  E D Saggerson; A L Greenbaum
Journal:  Biochem J       Date:  1970-09       Impact factor: 3.857

4.  Concentration of free oxaloacetate in the mitochondrial compartment of isolated liver cells.

Authors:  E A Siess; R I Kientsch-Engel; O H Wieland
Journal:  Biochem J       Date:  1984-02-15       Impact factor: 3.857

5.  The control of NAD specific malic enzyme from cauliflower bud mitochondria by metabolites.

Authors:  D D Davies; K D Patil
Journal:  Planta       Date:  1975-01       Impact factor: 4.116

6.  Th control of isocitrate oxidation by rat liver mitochondria.

Authors:  P B Nicholls DG RAND
Journal:  Biochem J       Date:  1969-09       Impact factor: 3.857

7.  Biochemical effects of the hypoglycaemic compound pent-4-enoic acid and related non-hypoglycaemic fatty acids. Oxidative phosphorylation and mitochondrial oxidation of pyruvate, 3-hydroxybutyrate and tricarboxylic acid-cycle intermediates.

Authors:  A E Senior; H S Sherratt
Journal:  Biochem J       Date:  1968-12       Impact factor: 3.857

8.  Serum and pancreatic juice carcinoembryonic antigen in pancreatic and biliary disease.

Authors:  D L Carr-Locke
Journal:  Gut       Date:  1980-08       Impact factor: 23.059

Review 9.  Impaired mitochondrial metabolism and mammary carcinogenesis.

Authors:  Nagendra Yadava; Sallie S Schneider; D Joseph Jerry; Chul Kim
Journal:  J Mammary Gland Biol Neoplasia       Date:  2012-12-27       Impact factor: 2.673

10.  p-Cymene pathway in Pseudomonas putida: ring cleavage of 2,3-dihydroxy-p-cumate and subsequent reactions.

Authors:  J J DeFrank; D W Ribbons
Journal:  J Bacteriol       Date:  1977-03       Impact factor: 3.490

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