Literature DB >> 429131

The Nb rat: prostatic adenocarcinoma model.

J R Drago, R M Ikeda, R E Maurer, L B Goldman, H Tesluk.   

Abstract

The Noble rat prostatic adenocarcinoma is an animal model which is used to study human prostatic carcinoma. It mimics the human condition in histology, in biochemistry with the production of acid phosphatase, and in tumor growth which is relatively constant. Additionally, it is hormonally dependent and metastasizes. This animal model should provide an avenue for the evaluation of cytotoxic chemotherapeutic agents heretofore receiving little attention from the urologic community.

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Year:  1979        PMID： 429131

Source DB:  PubMed          Journal:  Invest Urol        ISSN： 0021-0005


  5 in total

1.  Immunobiology and therapeutic manipulation of heterotransplanted Nb rat prostatic adenocarcinoma. Chemotherapy of autonomous tumor, 102 Pr, heterotransplanted into congenitally athymic (nude) mice and syngeneic Nb rats.

Authors:  J R Drago; R E Maurer; L B Goldman; M E Gershwin
Journal:  Cancer Chemother Pharmacol       Date:  1979       Impact factor: 3.333

2.  Treatment of an Nb-Pr-A.I.-3 (autonomous) tumor with combination chemotherapy.

Authors:  J R Drago; T Worgul
Journal:  Cancer Chemother Pharmacol       Date:  1981       Impact factor: 3.333

3.  Effect of very high dose D-leucine6-gonadotropin-releasing hormone proethylamide on the hypothalamic-pituitary testicular axis in patients with prostatic cancer.

Authors:  B Warner; T J Worgul; J Drago; L Demers; M Dufau; D Max; R J Santen
Journal:  J Clin Invest       Date:  1983-06       Impact factor: 14.808

4.  Loss of NADPH quinone oxidoreductase in the prostate and enhanced serum levels of cytokine-induced neutrophil chemoattractant 2alpha in hormone-stimulated noble rats: potential role in prostatic intraepithelial neoplasia development.

Authors:  Rita Ghosh; John Schoolfield; I-Tien Yeh; Maxwell L Smith; Stephen D Hursting; Daniel C Chan; M Scott Lucia; Addanki P Kumar
Journal:  Transl Oncol       Date:  2009-05       Impact factor: 4.243

Review 5.  Role of cadmium in carcinogenesis with special reference to cancer of the prostate.

Authors:  M Piscator
Journal:  Environ Health Perspect       Date:  1981-08       Impact factor: 9.031
  5 in total

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