| Literature DB >> 429104 |
M Stern, A Warshawsky, M Fridkin.
Abstract
2-Mercaptopyridine was used to effect the selective, mild and efficient cleavage of the o-nitrophenylsulphenyl amino-protecting group from several amino acids and peptides. By utilization of this reagent a stepwise synthesis of the tetrapeptide Thr-Lys-Leu-Arg([Leu3]tuftsin) was successfully achieved. The potential use of 2-mercaptopyridine in mechanized peptide synthesis via the polymeric reagents approach is discussed.Entities:
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Year: 1979 PMID： 429104 DOI： 10.1111/j.1399-3011.1979.tb01885.x
Source DB: PubMed Journal: Int J Pept Protein Res ISSN： 0367-8377