Literature DB >> 429089

Syntheses and biological activities of methoxinine-analogues of the C-terminal octapeptide of cholecystokinin-pancreozymin.

D Gillessen, A Trzeciak, R K Müller, R O Studer.   

Abstract

The C-terminal octapeptide of cholecystokinin-pancreozymin and its analogues in which the methionine residues were successively replaced by methoxinine have been synthesized. When these analogues were tested for their gallbladder-contraction activity in an in vitro system the following relative potencies were observed: [Mox3]-CCK-PZ 8 (95%), [Mox6]-CCK-PZ 8 (5%) and [Mox3, Mox6]-CCK-PZ 8 (2%).

Entities:  

Mesh：

Substances：

Year:  1979        PMID： 429089     DOI： 10.1111/j.1399-3011.1979.tb01860.x

Source DB:  PubMed          Journal:  Int J Pept Protein Res        ISSN： 0367-8377


  2 in total

1.  Protease-catalyzed peptide bond formation: application to synthesis of the COOH-terminal octapeptide of cholecystokinin.

Authors:  W Kullmann
Journal:  Proc Natl Acad Sci U S A       Date:  1982-05       Impact factor: 11.205

2.  Biological activity of the C-terminal octapeptide of cholecystokinin, of three of its analogues and of caerulein in the dog.

Authors:  F D Meyer; K Gyr; L Kayasseh; L Jeker; M Wall; A Trzeciak; D Gillessen
Journal:  Experientia       Date:  1980-04-15
  2 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.